The Y-chromosome F haplogroup contributes to the development of Barrett's esophagus-associated esophageal adenocarcinoma in a white male population

W. M. Westra; A. M. Rygiel; N. Mostafavi; G. M. J. de Wit; A. L. Roes; L. M. G. Moons; M. P. Peppelenbosch; S. Ouburg; S. A. Morre; M. Jacobs; P. D. Siersema; S. Repping; K. K. Wang; K. K. Krishnadath

doi:10.1093/dote/doaa011

The Y-chromosome F haplogroup contributes to the development of Barrett's esophagus-associated esophageal adenocarcinoma in a white male population

W. M. Westra, A. M. Rygiel, N. Mostafavi, G. M. J. de Wit, A. L. Roes, L. M. G. Moons, M. P. Peppelenbosch, S. Ouburg, S. A. Morre, M. Jacobs, P. D. Siersema, S. Repping, K. K. Wang, K. K. Krishnadath^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Web of Science)

Abstract

Barrett's esophagus (BE) is a metaplastic condition of the distal esophagus, resulting from longstanding gastroesophageal reflux disease (GERD). BE predisposes for the highly malignant esophageal adenocarcinoma (EAC). Both BE and EAC have the highest frequencies in white males. Only a subset of patients with GERD develop BE, while

Original language	English
Article number	011
Number of pages	6
Journal	Diseases of the Esophagus
Volume	33
Issue number	9
DOIs	https://doi.org/10.1093/dote/doaa011
Publication status	Published - Sep 2020

Keywords

Barrett's esophagus
esophageal adenocarcinoma
gastroesophageal reflux disease
genetic polymorphisms
Y-chromosome haplogroup
RISK-FACTORS
CIGARETTE-SMOKING
SUSCEPTIBILITY
POLYMORPHISM
CARCINOMA
MUTATION
DELETION
DISEASE

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10.1093/dote/doaa011Licence: CC BY-NC

Cite this

Westra, W. M., Rygiel, A. M., Mostafavi, N., de Wit, G. M. J., Roes, A. L., Moons, L. M. G., Peppelenbosch, M. P., Ouburg, S., Morre, S. A., Jacobs, M., Siersema, P. D., Repping, S., Wang, K. K., & Krishnadath, K. K. (2020). The Y-chromosome F haplogroup contributes to the development of Barrett's esophagus-associated esophageal adenocarcinoma in a white male population. Diseases of the Esophagus, 33(9), [011]. https://doi.org/10.1093/dote/doaa011

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title = "The Y-chromosome F haplogroup contributes to the development of Barrett's esophagus-associated esophageal adenocarcinoma in a white male population",

abstract = "Barrett's esophagus (BE) is a metaplastic condition of the distal esophagus, resulting from longstanding gastroesophageal reflux disease (GERD). BE predisposes for the highly malignant esophageal adenocarcinoma (EAC). Both BE and EAC have the highest frequencies in white males. Only a subset of patients with GERD develop BE, while",

keywords = "Barrett's esophagus, esophageal adenocarcinoma, gastroesophageal reflux disease, genetic polymorphisms, Y-chromosome haplogroup, RISK-FACTORS, CIGARETTE-SMOKING, SUSCEPTIBILITY, POLYMORPHISM, CARCINOMA, MUTATION, DELETION, DISEASE",

author = "Westra, {W. M.} and Rygiel, {A. M.} and N. Mostafavi and {de Wit}, {G. M. J.} and Roes, {A. L.} and Moons, {L. M. G.} and Peppelenbosch, {M. P.} and S. Ouburg and Morre, {S. A.} and M. Jacobs and Siersema, {P. D.} and S. Repping and Wang, {K. K.} and Krishnadath, {K. K.}",

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Westra, WM, Rygiel, AM, Mostafavi, N, de Wit, GMJ, Roes, AL, Moons, LMG, Peppelenbosch, MP, Ouburg, S, Morre, SA, Jacobs, M, Siersema, PD, Repping, S, Wang, KK & Krishnadath, KK 2020, 'The Y-chromosome F haplogroup contributes to the development of Barrett's esophagus-associated esophageal adenocarcinoma in a white male population', Diseases of the Esophagus, vol. 33, no. 9, 011. https://doi.org/10.1093/dote/doaa011

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T1 - The Y-chromosome F haplogroup contributes to the development of Barrett's esophagus-associated esophageal adenocarcinoma in a white male population

AU - Westra, W. M.

AU - Rygiel, A. M.

AU - Mostafavi, N.

AU - de Wit, G. M. J.

AU - Roes, A. L.

AU - Moons, L. M. G.

AU - Peppelenbosch, M. P.

AU - Ouburg, S.

AU - Morre, S. A.

AU - Jacobs, M.

AU - Siersema, P. D.

AU - Repping, S.

AU - Wang, K. K.

AU - Krishnadath, K. K.

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KW - Barrett's esophagus

KW - esophageal adenocarcinoma

KW - gastroesophageal reflux disease

KW - genetic polymorphisms

KW - Y-chromosome haplogroup

KW - RISK-FACTORS

KW - CIGARETTE-SMOKING

KW - SUSCEPTIBILITY

KW - POLYMORPHISM

KW - CARCINOMA

KW - MUTATION

KW - DELETION

KW - DISEASE

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