THE VELO-CARDIO-FACIAL SYNDROME: THE SPECTRUM OF PSYCHIATRIC PROBLEMS AND COGNITIVE DETERIORATION AT ADULT AGE

L. J. M. Evers*, C. E. M. De Die-Smulders, E. E. J. Smeets, M. G. M. Clerkx, L. M. G. Curfs

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The velo-cardio-facial syndrome: the spectrum of psychiatric problems and cognitive deterioration at adult age: Deletion 22q11.2 syndrome, or the velo-cardio-facial syndrome (VCFS), is a syndrome with a known but varied clinical and behavioral phenotype. We report 7 patients with 22q11.2 deletion syndrome and an intellectual disability. Aside from the described behavioral phenotype in literature, a moderate, severe or profound intellectual disability may be present. Special attention should be given to cognitive deterioration.
Original languageEnglish
Pages (from-to)307-316
JournalGenetic Counseling
Volume20
Issue number4
Publication statusPublished - 2009

Keywords

  • VCFS
  • Intellectual disability
  • Deletion 22q11.2
  • Cognitive deterioration

Cite this