The validity of the DSM-IV diagnostic classification system of non-affective psychoses

Nikie Korver-Nieberg*, Piotr J. Quee, Heleen B. M. Boos, C. Simons, Rene S. Kahn, Wiepke Cahn, Don H. Linszen, Lieuwe de Haan, Jim van Os, Lydia Krabbendam, Inez Myin-Germeys, Durk Wiersma, Richard Bruggemen, S. E. van den Berg, C. L. A. Schroeder, R. van der Valk, N. Dekker, Carin J. Meijer, L. N. Boyette, J. MeijerD. van Dam, I. de Rijke, S. Huinink, Sanne I. de Vries, M. Jansen, D. Bos, W. P. Hoen, E. M. te West, S. H. J. Groeneveld, E. M. Vergunst, Marije Swets, S. Vothknecht, I. Poleacov, D. van Dijk, D. Spruijt-Metz, M. T. Hasty, G. Geertsa, P. M. de Baaij, A. Metzger, Nico J. M. van Beveren, M. Baldini, F. D. Grimbergen, M. A. M. Boerma, C. Agsteribbe, H. P. Wisman, M. A. H. Monden, M. Bosman, M. van Dijk, Rianne M. C. Klaassen, M. T. C. Tang, L. B. Luteijn, H. Winkel, H. Weisz, A. C. P. Strater, A. Landman, Marc A. T. M. Vorstenbosch, D. Op 't Eijnde, K. Lenders, S. Loyen, R. Roberts, Kim Sweers, H. Gielen, N. Soons, A. Hintzen, C.D. Habets van der Poel, I. Riske, C. Vossen, E. Martens, S. Apers, L. Wijnhoven, E. Konings, T. Lataster, M. Lardinois, D. Versmissen, C. Simons, M. van der Werf, P. Habets, S. Pfeifer, E. de Loore, M. Heins, M. Oorschot, M. Meys, M. Dietvorst, C. van Zelst, I. Crolla, Ron Mengelers, F. van Goethem, W. Beuken, D. Byniam, T. Driesen, M. Marcelis, G. Driessen, A. Shazad, R. van Winkel, C. Henquet, G. Kenis, P. Delespaul, P. Anema, E. M. J. van Baaren, S. C. Bakker, E. Caspers, Eske M. Derks, S. van Hemert, A. Hemkes, Ron Hijman, M. van Leeuwen, J. E. H. Machielsen, Roel A. Ophoff, M. Rais, M. Salden, H. van Someren, E. Strengman, M. Vleesschouwer, M. van Beek, P. N. van Harten, Jeroen P. F. Koning, W. Schep, M. G. Vollema, Bram P Prins, T. Viester, A. Akdeniz, K. Verweij, K. Kaymaz, Frank Van den Heuvel, B. Van der Goot, J.E. Hovens, A. J. M. Loonen, J. Bous, M. Veenstra, E. van 't Hag, F. J. Nienhuis, H. G. O. M. Smid, E. Veermans, Agna A. Bartels-Velthuis, F. Duijndam, T. Lugtenberg, Henderikus Knegtering, W. Blaauw, A. Wunderink, K. P. Touw, J. Arends, Cees J. Slooff, J. Brilman, M. Schomaker, Michiel van Wijk, A. Wessels, E. Vroom, K. Meijerink, I. Bogert, W. Janssen, Inge A. H. van den Berk, E.O. Noorthoorn van der Kruijff, Helga K. Ising, Jan Dirk Blom, Mark van der Gaag, G. Mensen, R. van der Snoek, R. Smit, G. Faber

*Corresponding author for this work

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    19 Citations (Web of Science)

    Abstract

    Objective: The schizophrenia and other non-affective disorders categories listed in the DSM-IV, are currently under revision for the development of the fifth edition. The aim of the present study is to demonstrate the validity of these categories by investigating possible differences between diagnostic patient subgroups on various measures. Methods: 1064 patients with a diagnosis of non-affective psychosis (schizophrenia N = 731 (paranoid type 82%), schizoaffective N = 63, schizophreniform N = 120, psychosis not otherwise specified/brief psychotic disorder N = 150) participated in this study. Dependent variables were demographic and clinical characteristics, severity of psychopathology, premorbid and current functioning, and indicators of quality of life. Results: Within the diagnostic group of schizophrenia, no significant differences were observed between paranoid schizophrenia, disorganized, and undifferentiated schizophrenia. Patients with schizophrenia experienced more severe psychopathology and had poorer levels of current functioning compared to patients with psychosis not otherwise specified or brief psychotic disorder. Differences between schizophrenia and schizoaffective disorder were less clear. Conclusion: Our results do not support the validity of schizophrenia subtypes. Schizophrenia can be distinguished from brief psychotic disorder and psychotic disorder not otherwise specified. These findings may fuel the actual DSM-V discussion.
    Original languageEnglish
    Pages (from-to)1061-1068
    JournalAustralian and New Zealand Journal of Psychiatry
    Volume45
    Issue number12
    DOIs
    Publication statusPublished - Dec 2011

    Keywords

    • categorization
    • DSM-V
    • schizophrenia
    • subtypes
    • validity

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