The 'thousand-dollar genome': an ethical exploration

Wybo J. Dondorp*, Guido M. W. R. de Wert

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Sequencing an individual's complete genome is expected to be possible for a relatively low sum 'one thousand dollars' within a few years. Sequencing refers to determining the order of base pairs that make up the genome. The result is a library of three billion letter combinations. Cheap whole-genome sequencing is of greatest importance to medical scientific research. Comparing individual complete genomes will lead to a better understanding of the contribution genetic variation makes to health and disease. As knowledge increases, the 'thousand-dollar genome' will also become increasingly important to healthcare. The applications that come within reach raise a number of ethical questions. This monitoring report addresses the issue.
Original languageEnglish
Pages (from-to)S6-S26
JournalEuropean Journal of Human Genetics
Volume21
DOIs
Publication statusPublished - Jun 2013

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