The Subcellular Distribution of Ryanodine Receptors and L-Type Ca2+ Channels Modulates Ca2+-Transient Properties and Spontaneous Ca2+-Release Events in Atrial Cardiomyocytes

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number1108
Number of pages18
JournalFrontiers in physiology
Volume9
DOIs
Publication statusPublished - 14 Aug 2018

Keywords

  • calcium
  • sarcoplasmic reticulum
  • ryanodine receptor
  • spontaneous calcium releases
  • atrial fibrillation
  • subcellular distribution
  • computational modeling
  • AXIAL TUBULE SYSTEM
  • CALCIUM-RELEASE
  • SARCOPLASMIC-RETICULUM
  • NA+-CA2+ EXCHANGER
  • 3-DIMENSIONAL DISTRIBUTION
  • MOLECULAR-MECHANISMS
  • RYR2 PHOSPHORYLATION
  • TRIGGERED ACTIVITY
  • HEART-FAILURE
  • FIBRILLATION

Cite this

@article{249ba8c0ee3c4f5eb75a66e5080bb8d2,
title = "The Subcellular Distribution of Ryanodine Receptors and L-Type Ca2+ Channels Modulates Ca2+-Transient Properties and Spontaneous Ca2+-Release Events in Atrial Cardiomyocytes",
keywords = "calcium, sarcoplasmic reticulum, ryanodine receptor, spontaneous calcium releases, atrial fibrillation, subcellular distribution, computational modeling, AXIAL TUBULE SYSTEM, CALCIUM-RELEASE, SARCOPLASMIC-RETICULUM, NA+-CA2+ EXCHANGER, 3-DIMENSIONAL DISTRIBUTION, MOLECULAR-MECHANISMS, RYR2 PHOSPHORYLATION, TRIGGERED ACTIVITY, HEART-FAILURE, FIBRILLATION",
author = "Henry Sutanto and {van Sloun}, Bart and Patrick Sch{\"o}nleitner and {van Zandvoort}, {Marc A. M. J.} and Gudrun Antoons and Jordi Heijman",
year = "2018",
month = "8",
day = "14",
doi = "10.3389/fphys.2018.01108",
language = "English",
volume = "9",
journal = "Frontiers in physiology",
issn = "1664-042X",
publisher = "Frontiers Media S.A.",

}

TY - JOUR

T1 - The Subcellular Distribution of Ryanodine Receptors and L-Type Ca2+ Channels Modulates Ca2+-Transient Properties and Spontaneous Ca2+-Release Events in Atrial Cardiomyocytes

AU - Sutanto, Henry

AU - van Sloun, Bart

AU - Schönleitner, Patrick

AU - van Zandvoort, Marc A. M. J.

AU - Antoons, Gudrun

AU - Heijman, Jordi

PY - 2018/8/14

Y1 - 2018/8/14

KW - calcium

KW - sarcoplasmic reticulum

KW - ryanodine receptor

KW - spontaneous calcium releases

KW - atrial fibrillation

KW - subcellular distribution

KW - computational modeling

KW - AXIAL TUBULE SYSTEM

KW - CALCIUM-RELEASE

KW - SARCOPLASMIC-RETICULUM

KW - NA+-CA2+ EXCHANGER

KW - 3-DIMENSIONAL DISTRIBUTION

KW - MOLECULAR-MECHANISMS

KW - RYR2 PHOSPHORYLATION

KW - TRIGGERED ACTIVITY

KW - HEART-FAILURE

KW - FIBRILLATION

U2 - 10.3389/fphys.2018.01108

DO - 10.3389/fphys.2018.01108

M3 - Article

VL - 9

JO - Frontiers in physiology

JF - Frontiers in physiology

SN - 1664-042X

M1 - 1108

ER -