The structure-function relationship of activated protein C Lessons from natural and engineered mutations

Karin C. A. A. Wildhagen, Esther Lutgens, Sarah T. G. B. Loubele, Hugo ten Cate, Gerry A. F. Nicolaes*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

27 Citations (Web of Science)
Original languageEnglish
Pages (from-to)1034-1045
JournalThrombosis and Haemostasis
Issue number6
Publication statusPublished - Dec 2011


  • Activated protein C
  • anticoagulation
  • cytoprotection
  • mutagenesis
  • structure-function

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