The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis

Klaus P. Machold; Robert Landewe; Josef S. Smolen; Tanja A. Stamm; Desiree M. van der Heijde; Kirsten N. Verpoort; Kerstin Brickmann; Janitzia Vazquez-Mellado; Dimitri E. Karateev; Ferdinand C. Breedveld; Paul Emery; Thomas W. J. Huizinga

doi:10.1136/ard.2009.122473

The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis

Klaus P. Machold^*
, Robert Landewe
, Josef S. Smolen
, Tanja A. Stamm
, Desiree M. van der Heijde
, Kirsten N. Verpoort
, Kerstin Brickmann
, Janitzia Vazquez-Mellado
, Dimitri E. Karateev
, Ferdinand C. Breedveld
, Paul Emery
, Thomas W. J. Huizinga

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background Glucocorticoids (GCs) are often used as early arthritis treatment and it has been suggested that they induce remission or at least delay the development of rheumatoid arthritis (RA) and the need to start disease-modifying antirheumatic drugs (DMARDs). Objective To test the effect of GCs on patients with very early arthritis (symptom duration of

Original language	English
Pages (from-to)	495-502
Number of pages	8
Journal	Annals of the Rheumatic Diseases
Volume	69
Issue number	3
DOIs	https://doi.org/10.1136/ard.2009.122473
Publication status	Published - Mar 2010

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10.1136/ard.2009.122473

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Machold, K. P., Landewe, R., Smolen, J. S., Stamm, T. A., van der Heijde, D. M., Verpoort, K. N., Brickmann, K., Vazquez-Mellado, J., Karateev, D. E., Breedveld, F. C., Emery, P., & Huizinga, T. W. J. (2010). The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis. Annals of the Rheumatic Diseases, 69(3), 495-502. https://doi.org/10.1136/ard.2009.122473

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title = "The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis",

abstract = "Background Glucocorticoids (GCs) are often used as early arthritis treatment and it has been suggested that they induce remission or at least delay the development of rheumatoid arthritis (RA) and the need to start disease-modifying antirheumatic drugs (DMARDs). Objective To test the effect of GCs on patients with very early arthritis (symptom duration of ",

author = "Machold, \{Klaus P.\} and Robert Landewe and Smolen, \{Josef S.\} and Stamm, \{Tanja A.\} and \{van der Heijde\}, \{Desiree M.\} and Verpoort, \{Kirsten N.\} and Kerstin Brickmann and Janitzia Vazquez-Mellado and Karateev, \{Dimitri E.\} and Breedveld, \{Ferdinand C.\} and Paul Emery and Huizinga, \{Thomas W. J.\}",

year = "2010",

month = mar,

doi = "10.1136/ard.2009.122473",

language = "English",

volume = "69",

pages = "495--502",

journal = "Annals of the Rheumatic Diseases",

issn = "0003-4967",

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Machold, KP, Landewe, R, Smolen, JS, Stamm, TA, van der Heijde, DM, Verpoort, KN, Brickmann, K, Vazquez-Mellado, J, Karateev, DE, Breedveld, FC, Emery, P & Huizinga, TWJ 2010, 'The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis', Annals of the Rheumatic Diseases, vol. 69, no. 3, pp. 495-502. https://doi.org/10.1136/ard.2009.122473

The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis. / Machold, Klaus P.; Landewe, Robert; Smolen, Josef S. et al.
In: Annals of the Rheumatic Diseases, Vol. 69, No. 3, 03.2010, p. 495-502.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis

AU - Machold, Klaus P.

AU - Landewe, Robert

AU - Smolen, Josef S.

AU - Stamm, Tanja A.

AU - van der Heijde, Desiree M.

AU - Verpoort, Kirsten N.

AU - Brickmann, Kerstin

AU - Vazquez-Mellado, Janitzia

AU - Karateev, Dimitri E.

AU - Breedveld, Ferdinand C.

AU - Emery, Paul

AU - Huizinga, Thomas W. J.

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AB - Background Glucocorticoids (GCs) are often used as early arthritis treatment and it has been suggested that they induce remission or at least delay the development of rheumatoid arthritis (RA) and the need to start disease-modifying antirheumatic drugs (DMARDs). Objective To test the effect of GCs on patients with very early arthritis (symptom duration of

U2 - 10.1136/ard.2009.122473

DO - 10.1136/ard.2009.122473

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SN - 0003-4967

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SP - 495

EP - 502

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

IS - 3

ER -

The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis

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