The sensitivity of laboratory tests assessing driving related skills to dose-related impairment of alcohol: A literature review

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Abstract

Laboratory tests assessing driving related skills can be useful as initial screening tools to assess potential drug induced impairment as part of a standardized behavioural assessment. Unfortunately, consensus about which laboratory tests should be included to reliably assess drug induced impairment has not yet been reached. The aim of the present review was to evaluate the sensitivity of laboratory tests to the dose dependent effects of alcohol, as a benchmark, on performance parameters. In total, 179 experimental studies were included. Results show that a cued go/no-go task and a divided attention test with primary tracking and secondary visual search were consistently sensitive to the impairing effects at medium and high blood alcohol concentrations. Driving performance assessed in a simulator was less sensitive to the effects of alcohol as compared to naturalistic, on-the-road driving. In conclusion, replicating results of several potentially useful tests and their predictive validity of actual driving impairment should deserve further research. In addition, driving simulators should be validated and compared head to head to naturalistic driving in order to increase construct validity.
Original languageEnglish
Pages (from-to)31-48
Number of pages18
JournalAccident Analysis and Prevention
Volume89
DOIs
Publication statusPublished - Apr 2016

Keywords

  • Alcohol
  • Sensitivity
  • Reliability
  • Laboratory tests
  • Simulator driving
  • Actual driving
  • PLACEBO-CONTROLLED TRIAL
  • PURSUIT EYE-MOVEMENTS
  • RISK-TAKING BEHAVIOR
  • SLEEP LATENCY TEST
  • PSYCHOMOTOR PERFORMANCE
  • HEALTHY-VOLUNTEERS
  • TASK-PERFORMANCE
  • SOCIAL DRINKERS
  • SIMULATOR PERFORMANCE
  • DRIVER IMPAIRMENT

Cite this

@article{f9314d90b6fd470e8c36467c28e9b1f0,
title = "The sensitivity of laboratory tests assessing driving related skills to dose-related impairment of alcohol: A literature review",
abstract = "Laboratory tests assessing driving related skills can be useful as initial screening tools to assess potential drug induced impairment as part of a standardized behavioural assessment. Unfortunately, consensus about which laboratory tests should be included to reliably assess drug induced impairment has not yet been reached. The aim of the present review was to evaluate the sensitivity of laboratory tests to the dose dependent effects of alcohol, as a benchmark, on performance parameters. In total, 179 experimental studies were included. Results show that a cued go/no-go task and a divided attention test with primary tracking and secondary visual search were consistently sensitive to the impairing effects at medium and high blood alcohol concentrations. Driving performance assessed in a simulator was less sensitive to the effects of alcohol as compared to naturalistic, on-the-road driving. In conclusion, replicating results of several potentially useful tests and their predictive validity of actual driving impairment should deserve further research. In addition, driving simulators should be validated and compared head to head to naturalistic driving in order to increase construct validity.",
keywords = "Alcohol, Sensitivity, Reliability, Laboratory tests, Simulator driving, Actual driving, PLACEBO-CONTROLLED TRIAL, PURSUIT EYE-MOVEMENTS, RISK-TAKING BEHAVIOR, SLEEP LATENCY TEST, PSYCHOMOTOR PERFORMANCE, HEALTHY-VOLUNTEERS, TASK-PERFORMANCE, SOCIAL DRINKERS, SIMULATOR PERFORMANCE, DRIVER IMPAIRMENT",
author = "S Jongen and Vuurman, {E F P M} and Ramaekers, {J G} and A Vermeeren",
note = "Open Access",
year = "2016",
month = "4",
doi = "10.1016/j.aap.2016.01.001",
language = "English",
volume = "89",
pages = "31--48",
journal = "Accident Analysis and Prevention",
issn = "0001-4575",
publisher = "Elsevier Limited",

}

TY - JOUR

T1 - The sensitivity of laboratory tests assessing driving related skills to dose-related impairment of alcohol

T2 - A literature review

AU - Jongen, S

AU - Vuurman, E F P M

AU - Ramaekers, J G

AU - Vermeeren, A

N1 - Open Access

PY - 2016/4

Y1 - 2016/4

N2 - Laboratory tests assessing driving related skills can be useful as initial screening tools to assess potential drug induced impairment as part of a standardized behavioural assessment. Unfortunately, consensus about which laboratory tests should be included to reliably assess drug induced impairment has not yet been reached. The aim of the present review was to evaluate the sensitivity of laboratory tests to the dose dependent effects of alcohol, as a benchmark, on performance parameters. In total, 179 experimental studies were included. Results show that a cued go/no-go task and a divided attention test with primary tracking and secondary visual search were consistently sensitive to the impairing effects at medium and high blood alcohol concentrations. Driving performance assessed in a simulator was less sensitive to the effects of alcohol as compared to naturalistic, on-the-road driving. In conclusion, replicating results of several potentially useful tests and their predictive validity of actual driving impairment should deserve further research. In addition, driving simulators should be validated and compared head to head to naturalistic driving in order to increase construct validity.

AB - Laboratory tests assessing driving related skills can be useful as initial screening tools to assess potential drug induced impairment as part of a standardized behavioural assessment. Unfortunately, consensus about which laboratory tests should be included to reliably assess drug induced impairment has not yet been reached. The aim of the present review was to evaluate the sensitivity of laboratory tests to the dose dependent effects of alcohol, as a benchmark, on performance parameters. In total, 179 experimental studies were included. Results show that a cued go/no-go task and a divided attention test with primary tracking and secondary visual search were consistently sensitive to the impairing effects at medium and high blood alcohol concentrations. Driving performance assessed in a simulator was less sensitive to the effects of alcohol as compared to naturalistic, on-the-road driving. In conclusion, replicating results of several potentially useful tests and their predictive validity of actual driving impairment should deserve further research. In addition, driving simulators should be validated and compared head to head to naturalistic driving in order to increase construct validity.

KW - Alcohol

KW - Sensitivity

KW - Reliability

KW - Laboratory tests

KW - Simulator driving

KW - Actual driving

KW - PLACEBO-CONTROLLED TRIAL

KW - PURSUIT EYE-MOVEMENTS

KW - RISK-TAKING BEHAVIOR

KW - SLEEP LATENCY TEST

KW - PSYCHOMOTOR PERFORMANCE

KW - HEALTHY-VOLUNTEERS

KW - TASK-PERFORMANCE

KW - SOCIAL DRINKERS

KW - SIMULATOR PERFORMANCE

KW - DRIVER IMPAIRMENT

U2 - 10.1016/j.aap.2016.01.001

DO - 10.1016/j.aap.2016.01.001

M3 - Review article

C2 - 26802474

VL - 89

SP - 31

EP - 48

JO - Accident Analysis and Prevention

JF - Accident Analysis and Prevention

SN - 0001-4575

ER -