The role of red and processed meat in colorectal cancer development: a perspective

Marije Oostindjer*, Jan Alexander, Gro V. Amdam, Grethe Andersen, Nathan S. Bryan, Duan Chen, Denis E. Corpet, Stefaan De Smet, Lars Ove Dragsted, Anna Haug, Anders H. Karlsson, Gijs Kleter, Theo M. de Kok, Bard Kulseng, Andrew L. Milkowski, Roy J. Martin, Anne-Maria Pajari, Jan Erik Paulsen, Jana Pickova, Knut RudiMarianne Sodring, Douglas L. Weed, Bjorg Egelandsdal

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

This paper is based on a workshop held in Oslo, Norway in November 2013, in which experts discussed how to reach consensus on the healthiness of red and processed meat. Recent nutritional recommendations include reducing intake of red and processed meat to reduce cancer risk, in particular colorectal cancer (CRC). Epidemiological and mechanistic data on associations between red and processed meat intake and CRC are inconsistent and underlying mechanisms are unclear. There is a need for further studies on differences between white and red meat, between processed and whole red meat and between different types of processed meats, as potential health risks may not be the same for all products. Better biomarkers of meat intake and of cancer occurrence and updated food composition databases are required for future studies. Modifying meat composition via animal feeding and breeding, improving meat processing by alternative methods such as adding phytochemicals and improving our diets in general are strategies that need to be followed up.).
Original languageEnglish
Pages (from-to)583-596
JournalMeat Science
Volume97
Issue number4
DOIs
Publication statusPublished - Aug 2014

Keywords

  • Red meat
  • Processed meat
  • Colorectal cancer
  • Animal models
  • Epidemiology
  • Phytochemicals

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