The Role of Intracellular Trafficking of Notch Receptors in Ligand-Independent Notch Activation

J. Hounjet, M. Vooijs*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Article number1369
Number of pages23
JournalBiomolecules
Volume11
Issue number9
DOIs
Publication statusPublished - 1 Sep 2021

Keywords

  • Drosophila
  • Notch signaling
  • intracellular trafficking
  • ligand-independent
  • mammals
  • therapeutic targeting
  • GAMMA-SECRETASE INHIBITOR
  • PROTEOLYTIC ACTIVATION
  • TRANSMEMBRANE DOMAIN
  • AMYLOID PRECURSOR PROTEIN
  • ENDOCYTIC TRAFFICKING
  • ENDOSOMAL TRAFFICKING
  • DEPENDENT CLEAVAGE
  • RETROGRADE TRANSPORT
  • REGULATORY REGION
  • DROSOPHILA DELTEX

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