The Reproducibility of the Conversion of Nitrate to Nitrite in Human-saliva After a Nitrate Load

P. M. J. Bos, P. A. van den Brandt, M Wedel, Th. Ockhuizen

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

We investigated the reproducibility of the inter- and intra-individual variations in the conversion of nitrate to nitrite in saliva. Saliva samples were collected from 20 volunteers just before and at regular intervals after a nitrate load on four non-consecutive days within a period of 2 months. On three occasions beetroot juice was the nitrate source and on one occasion a nitrate solution was given. Despite large day-to-day variations it was possible to discriminate between subjects with a consistently high or low nitrate conversion after a nitrate load. Neither saliva sampling before a nitrate load nor single saliva samples are sufficient to obtain clear information about individual capacities for nitrate-nitrite conversion.
Original languageEnglish
Pages (from-to)93-97
Number of pages5
JournalFood and Chemical Toxicology
Volume26
Issue number2
DOIs
Publication statusPublished - Feb 1988

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