The relevance of applying exercise training principles when designing therapeutic interventions for patients with inflammatory myopathies: a systematic review

Pierrette Baschung Pfister*, Eling D. de Bruin, Bernadette C. Tobler-Ammann, Britta Maurer, Ruud H. Knols

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Physical exercise seems to be a safe and effective intervention in patients with inflammatory myopathy (IM). However, the optimal training intervention is not clear. To achieve an optimum training effect, physical exercise training principles must be considered and to replicate research findings, FITT components (frequency, intensity, time, and type) of exercise training should be reported. This review aims to evaluate exercise interventions in studies with IM patients in relation to (1) the application of principles of exercise training, (2) the reporting of FITT components, (3) the adherence of participants to the intervention, and (4) to assess the methodological quality of the included studies. The literature was searched for exercise studies in IM patients. Data were extracted to evaluate the application of the training principles, the reporting of and the adherence to the exercise prescription. The Downs and Black checklist was used to assess methodological quality of the included studies. From the 14 included studies, four focused on resistance, two on endurance, and eight on combined training. In terms of principles of exercise training, 93 % reported specificity, 50 % progression and overload, and 79 % initial values. Reversibility and diminishing returns were never reported. Six articles reported all FITT components in the prescription of the training though no study described adherence to all of these components. Incomplete application of the exercise training principles and insufficient reporting of the exercise intervention prescribed and completed hamper the reproducibility of the intervention and the ability to determine the optimal dose of exercise.
Original languageEnglish
Pages (from-to)1641-1654
JournalRheumatology International
Issue number10
Publication statusPublished - Oct 2015


  • Myositis
  • Inflammatory myopathy
  • Aerobic exercise
  • Resistance training
  • Training principles
  • Training components

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