The prediabetes conundrum: striking the balance between risk and resources

M.B. Blond*, K. Faerch*, C. Herder*, D. Ziegler*, C.D.A. Stehouwer*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare systems in the future, necessitating action from legislators and healthcare providers. But how do we best reduce its associated burden on health? As a compromise between differing opinions in the literature and among the authors of this article, we suggest stratifying individuals with prediabetes according to estimated risk and only offering individual-level preventive interventions to those at high risk. At the same time, we argue to identify those with prediabetes and already established diabetes-related complications and treat them as we would treat individuals with established type 2 diabetes.
Original languageEnglish
Pages (from-to)1016-1023
Number of pages8
JournalDiabetologia
Volume66
Issue number6
Early online date1 Mar 2023
DOIs
Publication statusPublished - Jun 2023

Keywords

  • Intermediate hyperglycaemia
  • Prediabetes
  • Risk
  • Stratified medicine
  • PLASMA-GLUCOSE LEVELS
  • DIABETES PREVENTION
  • PREVALENCE
  • DIAGNOSIS
  • RECOMMENDATIONS
  • INTERVENTIONS
  • INDIVIDUALS
  • POPULATION
  • MELLITUS
  • CRITERIA

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