The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity

Ligia Mendes Soares; Erika Meyer; Humberto Milani; Harry W. M. Steinbusch; Jos Prickaerts; Rubia M. Weffort de Oliveira

doi:10.1111/ejn.13461

The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity

Ligia Mendes Soares, Erika Meyer, Humberto Milani, Harry W. M. Steinbusch, Jos Prickaerts, Rubia M. Weffort de Oliveira^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	510-520
Number of pages	11
Journal	European Journal of Neuroscience
Volume	45
Issue number	4
DOIs	https://doi.org/10.1111/ejn.13461
Publication status	Published - Feb 2017

Keywords

antidepressant
anxiolytic
cognition
global brain ischemia
phosphodiesterase 2 inhibitor
TRANSIENT FOREBRAIN ISCHEMIA
ELEMENT-BINDING PROTEIN
CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES
CEREBRAL-BLOOD-FLOW
ELEVATED PLUS-MAZE
LONG-TERM-MEMORY
NITRIC-OXIDE
NEUROTROPHIC FACTOR
ALZHEIMERS-DISEASE
ANXIOLYTIC-LIKE

Access to Document

10.1111/ejn.13461

Cite this

Soares, L. M., Meyer, E., Milani, H., Steinbusch, H. W. M., Prickaerts, J., & de Oliveira, R. M. W. (2017). The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity. European Journal of Neuroscience, 45(4), 510-520. https://doi.org/10.1111/ejn.13461

Soares, Ligia Mendes ; Meyer, Erika ; Milani, Humberto ; Steinbusch, Harry W. M. ; Prickaerts, Jos ; de Oliveira, Rubia M. Weffort. / The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity. In: European Journal of Neuroscience. 2017 ; Vol. 45, No. 4. pp. 510-520.

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title = "The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity",

keywords = "antidepressant, anxiolytic, cognition, global brain ischemia, phosphodiesterase 2 inhibitor, TRANSIENT FOREBRAIN ISCHEMIA, ELEMENT-BINDING PROTEIN, CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES, CEREBRAL-BLOOD-FLOW, ELEVATED PLUS-MAZE, LONG-TERM-MEMORY, NITRIC-OXIDE, NEUROTROPHIC FACTOR, ALZHEIMERS-DISEASE, ANXIOLYTIC-LIKE",

author = "Soares, {Ligia Mendes} and Erika Meyer and Humberto Milani and Steinbusch, {Harry W. M.} and Jos Prickaerts and {de Oliveira}, {Rubia M. Weffort}",

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Soares, LM, Meyer, E, Milani, H, Steinbusch, HWM , Prickaerts, J & de Oliveira, RMW 2017, 'The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity', European Journal of Neuroscience, vol. 45, no. 4, pp. 510-520. https://doi.org/10.1111/ejn.13461

The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity. / Soares, Ligia Mendes; Meyer, Erika; Milani, Humberto; Steinbusch, Harry W. M.; Prickaerts, Jos; de Oliveira, Rubia M. Weffort.

In: European Journal of Neuroscience, Vol. 45, No. 4, 02.2017, p. 510-520.

Research output: Contribution to journal › Article › Academic › peer-review

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KW - ELEVATED PLUS-MAZE

KW - LONG-TERM-MEMORY

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