The phosphodiesterase-4 inhibitor rolipram protects from ischemic stroke in mice by reducing blood-brain-barrier damage, inflammation and thrombosis

Peter Kraft, Tobias Schwarz, Eva Goeb, Nadine Heydenreich, Marc Brede, Sven G. Meuth, Christoph Kleinschnitz

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)80-90
JournalExperimental Neurology
Volume247
DOIs
Publication statusPublished - Sep 2013

Keywords

  • Blood-brain-barrier
  • Phosphodiesterase inhibitor
  • Rolipram
  • Inflammation
  • Middle cerebral artery occlusion
  • Edema
  • Apoptosis
  • Thrombosis
  • Cytokines
  • Stroke

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