The Network Library: a framework to rapidly integrate network biology resources

Georg Summer; Thomas Kelder; Marijana Radonjic; Marc van Bilsen; Suzan Wopereis; Stephane Heymans

doi:10.1093/bioinformatics/btw436

The Network Library: a framework to rapidly integrate network biology resources

Georg Summer^*, Thomas Kelder, Marijana Radonjic, Marc van Bilsen, Suzan Wopereis, Stephane Heymans

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

6 Citations (Web of Science)

Abstract

Motivation: Much of the biological knowledge accumulated over the last decades is stored in different databases governed by various organizations and institutes. Integrating and connecting these vast knowledge repositories is an extremely useful method to support life sciences research and help formulate novel hypotheses. Results: We developed the Network Library (NL), a framework and toolset to rapidly integrate different knowledge sources to build a network biology resource that matches a specific research question. As a use-case we explore the interactions of genes related to heart failure with miRNAs and diseases through the integration of 6 databases.

Original language	English
Pages (from-to)	473-478
Journal	Bioinformatics
Volume	32
Issue number	17
DOIs	https://doi.org/10.1093/bioinformatics/btw436
Publication status	Published - 1 Sept 2016

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10.1093/bioinformatics/btw436

Cite this

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AU - Wopereis, Suzan

AU - Heymans, Stephane

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