The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1

M. G. A. van Eupen, M. T. Schram, H. M. Colhoun, N. M. J. Hanssen, H. W. M. Niessen, L. Tarnow, H. H. Parving, P. Rossing, C. D. A. Stehouwer, C. G. Schalkwijk*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1845-1855
Issue number8
Publication statusPublished - Aug 2013


  • Advanced glycation end-products
  • Atherosclerosis
  • Cardiovascular disease
  • Endothelial dysfunction
  • Macrovascular complications
  • Methylglyoxal
  • Microvascular complications
  • Soluble vascular cell adhesion molecule
  • Tetrahydropyrimidine
  • Type 1 diabetes mellitus

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