The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1

M. G. A. van Eupen, M. T. Schram, H. M. Colhoun, N. M. J. Hanssen, H. W. M. Niessen, L. Tarnow, H. H. Parving, P. Rossing, C. D. A. Stehouwer, C. G. Schalkwijk

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1845-1855
Issue number8
Publication statusPublished - Aug 2013


  • Advanced glycation end-products
  • Atherosclerosis
  • Cardiovascular disease
  • Endothelial dysfunction
  • Macrovascular complications
  • Methylglyoxal
  • Microvascular complications
  • Soluble vascular cell adhesion molecule
  • Tetrahydropyrimidine
  • Type 1 diabetes mellitus

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