The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy

Amin Damanafshan, Ies Elzenaar, Benoit Samson-Couterie, Ingeborg van der Made, Meriem Bourajjaj, Maarten M. van den Hoogenhof, Henk A. van Veen, Daisy I. Picavet, Abdelaziz Beqqali, Elisabeth Ehler, Leon J. DeWindt, Yigal M. Pinto, Ralph J. van Oort

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1474-1486
Number of pages13
JournalCardiovascular Research
Volume114
Issue number11
DOIs
Publication statusPublished - 1 Sep 2018

Keywords

  • Heart failure
  • Sarcomere
  • MEF2
  • DMPK
  • DYSTROPHY PROTEIN-KINASE
  • SERUM RESPONSE FACTOR
  • MYOTONIC-DYSTROPHY
  • HEART-FAILURE
  • DILATED CARDIOMYOPATHY
  • GENE-EXPRESSION
  • CARDIAC-HYPERTROPHY
  • SIGNALING PATHWAYS
  • MICE
  • PHOSPHORYLATION

Cite this

Damanafshan, A., Elzenaar, I., Samson-Couterie, B., van der Made, I., Bourajjaj, M., van den Hoogenhof, M. M., van Veen, H. A., Picavet, D. I., Beqqali, A., Ehler, E., DeWindt, L. J., Pinto, Y. M., & van Oort, R. J. (2018). The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy. Cardiovascular Research, 114(11), 1474-1486. https://doi.org/10.1093/cvr/cvy091