The journey of resveratrol from yeast to human.

S. Timmers, J. Auwerx, P. Schrauwen

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lower organisms. Given the worldwide increase in age-related metabolic diseases the beneficial effects of resveratrol on metabolism and healthy aging in humans are currently a topic of intense investigation.
Original languageEnglish
Pages (from-to)146-158
JournalAging
Volume4
Issue number3
DOIs
Publication statusPublished - 1 Jan 2012

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