Abstract
The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lower organisms. Given the worldwide increase in age-related metabolic diseases the beneficial effects of resveratrol on metabolism and healthy aging in humans are currently a topic of intense investigation.
Original language | English |
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Pages (from-to) | 146-158 |
Journal | Aging |
Volume | 4 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Jan 2012 |