@article{96793f499f8c4a038633cb45f2539f13,
title = "The International Atomic Energy Agency International Doubly Labelled Water Database: Aims, Scope and Procedures",
abstract = "Background: The doubly labelled water (DLW) method is an isotope-based technique that quantifies total energy expenditure (TEE) over periods of 1-3 weeks from the differential elimination of stable isotopes of oxygen and hydrogen. The method was invented in the 1950s, but limited ability to measure low isotope enrichments combined with the high cost of isotopes meant it only became feasible to use in humans in the 1980s. It is still relatively expensive to use, and alone small samples are unable to tackle some of the important questions surrounding energy balance such as how have expenditures changed over time and how do expenditures differ with age, between sexes and in different environments? Summary: By combining information across studies, answers to such questions may be possible. The International Atomic Energy Agency (IAEA) DLW database was established to pool DLW data across multiple studies. It was initiated by the main labs currently using the method and is hosted by the IAEA. At present, the database contains 6,621 measures of TEE by DLW from individuals in 23 countries, along with various additional data on the study participants. Key Messages: The IAEA DLW database is a key resource enabling future studies of energy demands.",
keywords = "Energy expenditure, Doubly labelled water, Nutrition, Obesity, Food requirements, EXPENDITURE, HUMANS",
author = "Speakman, {John R.} and Herman Pontzer and Jennifer Rood and Hiroyuki Sagayama and Schoeller, {Dale A.} and Westerterp, {Klaas R.} and Wong, {William W.} and Yosuke Yamada and Cornelia Loechl and Murphy-Alford, {Alexia J.}",
note = "Funding Information: half. The authors also gratefully acknowledge funding from the US National Science Foundation (BCS-1824466) awarded to Herman Pontzer. The funders played no role in the content of this manuscript. Funding Information: The article is part of the Proceedings of the International Symposium on Understanding the Double Burden of Malnutrition for Effective Interventions organized by the International Atomic Energy Agency (IAEA) in cooperation with United Nations Children{\textquoteleft}s Fund (UNICEF) and World Health Organization (WHO) (10–13 December 2018, Vienna, Austria). Funding Information: The database is generously supported by the IAEA and by the companies Taiyo Nippon Sanso, SERCON and ISOTEC. We are grateful to these companies for their support and especially to Ta-kashi Oono for his tremendous efforts at fund raising on our be- Funding Information: aInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China; bInstitute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, UK; cEvolutionary Anthropology, Duke University, Durham, NC, USA; dDuke Global Health Institute, Duke University, Durham, NC, USA; ePennington Biomedical Research Center, Baton Rouge, LA, USA; fFaculty of Health and Sports Sciences, University of Tsukuba, Tsukuba, Japan; gBiotechnology Center and Nutritional Sciences, University of Wisconsin, Madison, WI, USA; hNutrition and Translational Research in Metabolism, University of Maastricht, Maastricht, The Netherlands; iUSDA/ ARS Children{\textquoteright}s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; jNational Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan; kDivision of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria Publisher Copyright: {\textcopyright} 2019 International Atomic Energy Agency 2019 Published by S. Karger AG, Basel.; IAEA-UNICEF-WHO International Symposium on Understanding the Double Burden of Malnutrition for Effective Interventions ; Conference date: 10-12-2018 Through 13-12-2018",
year = "2019",
month = dec,
doi = "10.1159/000503668",
language = "English",
volume = "75",
pages = "114--118",
journal = "Annals of Nutrition and Metabolism",
issn = "0250-6807",
publisher = "Karger",
number = "2",
}