The Importance of Muscle Capillarization for Optimizing Satellite Cell Plasticity

J.P. Nederveen; M.W. Betz; T. Snijders; G. Parise

doi:10.1249/JES.0000000000000270

The Importance of Muscle Capillarization for Optimizing Satellite Cell Plasticity

J.P. Nederveen, M.W. Betz, T. Snijders, G. Parise^*

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

247 Downloads (Pure)

Abstract

Satellite cells are essential for skeletal muscle regeneration, repair, and adaptation. The activity of satellite cells is influenced by their interactions with muscle-resident endothelial cells. We postulate that the microvascular network between muscle fibers plays a critical role in satellite cell function. Exercise-induced angiogenesis can mitigate the decline in satellite cell function with age.

Original language	English
Pages (from-to)	284-290
Number of pages	7
Journal	Exercise and Sport Sciences Reviews
Volume	49
Issue number	4
DOIs	https://doi.org/10.1249/JES.0000000000000270
Publication status	Published - 1 Oct 2021

Keywords

satellite cells
capillarization
endothelial cells
skeletal muscle
regeneration
HUMAN SKELETAL-MUSCLE
RESISTANCE EXERCISE
ENDOTHELIAL-CELLS
REGENERATION
VEGF
ANGIOGENESIS
AGE
REJUVENATION
MYOGENESIS
EXPANSION

Access to Document

10.1249/JES.0000000000000270

Full text Final published version, 891 KBLicence: Taverne

Cite this

@article{cfbc9c52a3a34a22a8c75d141b7e0e8f,

title = "The Importance of Muscle Capillarization for Optimizing Satellite Cell Plasticity",

abstract = "Satellite cells are essential for skeletal muscle regeneration, repair, and adaptation. The activity of satellite cells is influenced by their interactions with muscle-resident endothelial cells. We postulate that the microvascular network between muscle fibers plays a critical role in satellite cell function. Exercise-induced angiogenesis can mitigate the decline in satellite cell function with age.",

keywords = "satellite cells, capillarization, endothelial cells, skeletal muscle, regeneration, HUMAN SKELETAL-MUSCLE, RESISTANCE EXERCISE, ENDOTHELIAL-CELLS, REGENERATION, VEGF, ANGIOGENESIS, AGE, REJUVENATION, MYOGENESIS, EXPANSION",

author = "J.P. Nederveen and M.W. Betz and T. Snijders and G. Parise",

note = "Publisher Copyright: Copyright {\textcopyright} 2021 by the American College of Sports Medicine.",

year = "2021",

month = oct,

day = "1",

doi = "10.1249/JES.0000000000000270",

language = "English",

volume = "49",

pages = "284--290",

journal = "Exercise and Sport Sciences Reviews",

issn = "0091-6331",

publisher = "LIPPINCOTT WILLIAMS & WILKINS",

number = "4",

}

TY - JOUR

T1 - The Importance of Muscle Capillarization for Optimizing Satellite Cell Plasticity

AU - Nederveen, J.P.

AU - Betz, M.W.

AU - Snijders, T.

AU - Parise, G.

PY - 2021/10/1

Y1 - 2021/10/1

N2 - Satellite cells are essential for skeletal muscle regeneration, repair, and adaptation. The activity of satellite cells is influenced by their interactions with muscle-resident endothelial cells. We postulate that the microvascular network between muscle fibers plays a critical role in satellite cell function. Exercise-induced angiogenesis can mitigate the decline in satellite cell function with age.

AB - Satellite cells are essential for skeletal muscle regeneration, repair, and adaptation. The activity of satellite cells is influenced by their interactions with muscle-resident endothelial cells. We postulate that the microvascular network between muscle fibers plays a critical role in satellite cell function. Exercise-induced angiogenesis can mitigate the decline in satellite cell function with age.

KW - satellite cells

KW - capillarization

KW - endothelial cells

KW - skeletal muscle

KW - regeneration

KW - HUMAN SKELETAL-MUSCLE

KW - RESISTANCE EXERCISE

KW - ENDOTHELIAL-CELLS

KW - REGENERATION

KW - VEGF

KW - ANGIOGENESIS

KW - AGE

KW - REJUVENATION

KW - MYOGENESIS

KW - EXPANSION

U2 - 10.1249/JES.0000000000000270

DO - 10.1249/JES.0000000000000270

M3 - (Systematic) Review article

C2 - 34547761

SN - 0091-6331

VL - 49

SP - 284

EP - 290

JO - Exercise and Sport Sciences Reviews

JF - Exercise and Sport Sciences Reviews

IS - 4

ER -