The impact of surgical aortic valve replacement on quality of life-a multicenter study

Fredrike Blokzijl; Saskia Houterman; Bart H M van Straten; Edgar Daeter; George J Brandon Bravo Bruinsma; Willem Dieperink; Michiel F Reneman; Frederik Keus; Iwan C C van der Horst; Massimo A Mariani

doi:10.1016/j.jtcvs.2019.09.184

The impact of surgical aortic valve replacement on quality of life-a multicenter study

Fredrike Blokzijl^*, Saskia Houterman, Bart H M van Straten, Edgar Daeter, George J Brandon Bravo Bruinsma, Willem Dieperink, Michiel F Reneman, Frederik Keus, Iwan C C van der Horst, Massimo A Mariani

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

OBJECTIVES: To explore the effect of surgical aortic valve replacement on quality of life and the variance with age, particularly in patients at risk of deterioration.

METHODS: In an observational, multicenter, cohort study of routinely collected health data, patients undergoing and electively operated between January 2011 and January 2015 with pre- and postoperative quality of life data were included. Patients were classified into 3 age groups: <65, 65-79, and ≥80 years. Quality of life was measured at baseline and at 1-year follow-up using the Short-Form Health Survey-12 or SF-36. We defined a >5-point difference as a minimal clinically important difference. Multivariable linear regression analysis, with adjustment for confounders, was used to evaluate the association between age and quality of life.

RESULTS: In 899 patients, mean physical health increased from 55 to 66 and mental health from 60 to 66. A minimal clinically important decreased physical health was observed in 12% of patients aged <65 years, 16% of patients aged 65-79 years, and 22% of patients aged ≥80 years (P = .023). A decreased mental health was observed in 15% of patients aged <65 years, 22% of patients aged 65-79 years, and 24% aged ≥80 years (P = .030). Older age and a greater physical and mental score at baseline were associated with a decreased physical and mental quality of life (P < .001).

CONCLUSIONS: Patients surviving surgical aortic valve replacement on average improve in physical and mental quality of life; nonetheless, with increasing age patients are at higher risk of experiencing a deterioration.

Original language	English
Pages (from-to)	1204-1210.e7
Number of pages	14
Journal	Journal of Thoracic and Cardiovascular Surgery
Volume	161
Issue number	4
Early online date	31 Oct 2019
DOIs	https://doi.org/10.1016/j.jtcvs.2019.09.184
Publication status	Published - Apr 2021

Keywords

surgical aortic valve replacement
quality of life
patient-reported outcomes

Access to Document

10.1016/j.jtcvs.2019.09.184Licence: Free access - publisher

Cite this

Blokzijl, F., Houterman, S., van Straten, B. H. M., Daeter, E., Brandon Bravo Bruinsma, G. J., Dieperink, W., Reneman, M. F., Keus, F., van der Horst, I. C. C., & Mariani, M. A. (2021). The impact of surgical aortic valve replacement on quality of life-a multicenter study. Journal of Thoracic and Cardiovascular Surgery, 161(4), 1204-1210.e7. https://doi.org/10.1016/j.jtcvs.2019.09.184

@article{9be53ab0c5fd485bb0a82855bf669694,

title = "The impact of surgical aortic valve replacement on quality of life-a multicenter study",

abstract = "OBJECTIVES: To explore the effect of surgical aortic valve replacement on quality of life and the variance with age, particularly in patients at risk of deterioration.METHODS: In an observational, multicenter, cohort study of routinely collected health data, patients undergoing and electively operated between January 2011 and January 2015 with pre- and postoperative quality of life data were included. Patients were classified into 3 age groups: <65, 65-79, and ≥80 years. Quality of life was measured at baseline and at 1-year follow-up using the Short-Form Health Survey-12 or SF-36. We defined a >5-point difference as a minimal clinically important difference. Multivariable linear regression analysis, with adjustment for confounders, was used to evaluate the association between age and quality of life.RESULTS: In 899 patients, mean physical health increased from 55 to 66 and mental health from 60 to 66. A minimal clinically important decreased physical health was observed in 12% of patients aged <65 years, 16% of patients aged 65-79 years, and 22% of patients aged ≥80 years (P = .023). A decreased mental health was observed in 15% of patients aged <65 years, 22% of patients aged 65-79 years, and 24% aged ≥80 years (P = .030). Older age and a greater physical and mental score at baseline were associated with a decreased physical and mental quality of life (P < .001).CONCLUSIONS: Patients surviving surgical aortic valve replacement on average improve in physical and mental quality of life; nonetheless, with increasing age patients are at higher risk of experiencing a deterioration.",

keywords = "surgical aortic valve replacement, quality of life, patient-reported outcomes",

author = "Fredrike Blokzijl and Saskia Houterman and {van Straten}, {Bart H M} and Edgar Daeter and {Brandon Bravo Bruinsma}, {George J} and Willem Dieperink and Reneman, {Michiel F} and Frederik Keus and {van der Horst}, {Iwan C C} and Mariani, {Massimo A}",

year = "2021",

month = apr,

doi = "10.1016/j.jtcvs.2019.09.184",

language = "English",

volume = "161",

pages = "1204--1210.e7",

journal = "Journal of Thoracic and Cardiovascular Surgery",

issn = "0022-5223",

publisher = "MOSBY-ELSEVIER",

number = "4",

}

Blokzijl, F, Houterman, S, van Straten, BHM, Daeter, E, Brandon Bravo Bruinsma, GJ, Dieperink, W, Reneman, MF, Keus, F, van der Horst, ICC & Mariani, MA 2021, 'The impact of surgical aortic valve replacement on quality of life-a multicenter study', Journal of Thoracic and Cardiovascular Surgery, vol. 161, no. 4, pp. 1204-1210.e7. https://doi.org/10.1016/j.jtcvs.2019.09.184

TY - JOUR

T1 - The impact of surgical aortic valve replacement on quality of life-a multicenter study

AU - Blokzijl, Fredrike

AU - Houterman, Saskia

AU - van Straten, Bart H M

AU - Daeter, Edgar

AU - Brandon Bravo Bruinsma, George J

AU - Dieperink, Willem

AU - Reneman, Michiel F

AU - Keus, Frederik

AU - van der Horst, Iwan C C

AU - Mariani, Massimo A

PY - 2021/4

Y1 - 2021/4

N2 - OBJECTIVES: To explore the effect of surgical aortic valve replacement on quality of life and the variance with age, particularly in patients at risk of deterioration.METHODS: In an observational, multicenter, cohort study of routinely collected health data, patients undergoing and electively operated between January 2011 and January 2015 with pre- and postoperative quality of life data were included. Patients were classified into 3 age groups: <65, 65-79, and ≥80 years. Quality of life was measured at baseline and at 1-year follow-up using the Short-Form Health Survey-12 or SF-36. We defined a >5-point difference as a minimal clinically important difference. Multivariable linear regression analysis, with adjustment for confounders, was used to evaluate the association between age and quality of life.RESULTS: In 899 patients, mean physical health increased from 55 to 66 and mental health from 60 to 66. A minimal clinically important decreased physical health was observed in 12% of patients aged <65 years, 16% of patients aged 65-79 years, and 22% of patients aged ≥80 years (P = .023). A decreased mental health was observed in 15% of patients aged <65 years, 22% of patients aged 65-79 years, and 24% aged ≥80 years (P = .030). Older age and a greater physical and mental score at baseline were associated with a decreased physical and mental quality of life (P < .001).CONCLUSIONS: Patients surviving surgical aortic valve replacement on average improve in physical and mental quality of life; nonetheless, with increasing age patients are at higher risk of experiencing a deterioration.

AB - OBJECTIVES: To explore the effect of surgical aortic valve replacement on quality of life and the variance with age, particularly in patients at risk of deterioration.METHODS: In an observational, multicenter, cohort study of routinely collected health data, patients undergoing and electively operated between January 2011 and January 2015 with pre- and postoperative quality of life data were included. Patients were classified into 3 age groups: <65, 65-79, and ≥80 years. Quality of life was measured at baseline and at 1-year follow-up using the Short-Form Health Survey-12 or SF-36. We defined a >5-point difference as a minimal clinically important difference. Multivariable linear regression analysis, with adjustment for confounders, was used to evaluate the association between age and quality of life.RESULTS: In 899 patients, mean physical health increased from 55 to 66 and mental health from 60 to 66. A minimal clinically important decreased physical health was observed in 12% of patients aged <65 years, 16% of patients aged 65-79 years, and 22% of patients aged ≥80 years (P = .023). A decreased mental health was observed in 15% of patients aged <65 years, 22% of patients aged 65-79 years, and 24% aged ≥80 years (P = .030). Older age and a greater physical and mental score at baseline were associated with a decreased physical and mental quality of life (P < .001).CONCLUSIONS: Patients surviving surgical aortic valve replacement on average improve in physical and mental quality of life; nonetheless, with increasing age patients are at higher risk of experiencing a deterioration.

KW - surgical aortic valve replacement

KW - quality of life

KW - patient-reported outcomes

U2 - 10.1016/j.jtcvs.2019.09.184

DO - 10.1016/j.jtcvs.2019.09.184

M3 - Article

C2 - 31839233

SN - 0022-5223

VL - 161

SP - 1204-1210.e7

JO - Journal of Thoracic and Cardiovascular Surgery

JF - Journal of Thoracic and Cardiovascular Surgery

IS - 4

ER -