The impact of personalized medicine of Type 2 diabetes mellitus in the global health context

Pierre Paul Michel Thomas, Salih Mohammed Alshehri, Henk J. van Kranen, Elena Ambrosino*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Web of Science)


Advances in the fields of genomic sciences have given rise to personalized medicine. This new paradigm draws upon a patient's genetic and metabolic makeup in order to tailor diagnostics and treatment. Personalized medicine holds remarkable promises to improve prevention and management of chronic diseases of global relevance, such as Type 2 diabetes mellitus (T2DM). This review article aims at summarizing the evidence from genome-based sciences on T2DM risk and management in different populations and in the Global Health context. Opinions from leading experts in the field were also included. Based on these findings, strengths and weaknesses of personalized approach to T2DM in a global context are delineated. Implications for future research and implementation on that subject are discussed.
Original languageEnglish
Pages (from-to)381-393
JournalPersonalized Medicine
Issue number4
Publication statusPublished - Jul 2016


  • genomics
  • global health
  • Type 2 diabetes mellitus

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