The impact of interpregnancy weight change on perinatal outcomes in women and their children: A systematic review and meta-analysis

Yvon E. G. Timmermans; Kim D. G. van de Kant; Elise O. Oosterman; Marc E. A. Spaanderman; Eduardo Villamor-Martinez; Jos Kleijnen; Anita C. E. Vreugdenhil

doi:10.1111/obr.12974

The impact of interpregnancy weight change on perinatal outcomes in women and their children: A systematic review and meta-analysis

Yvon E. G. Timmermans, Kim D. G. van de Kant, Elise O. Oosterman, Marc E. A. Spaanderman, Eduardo Villamor-Martinez, Jos Kleijnen, Anita C. E. Vreugdenhil^*

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

Prepregnancy overweight and obesity are associated with higher risk of perinatal complications. However, the effect of weight change prior to pregnancy on perinatal outcome is largely unknown. Therefore, it is aimed to examine the impact on perinatal outcomes of interpregnancy BMI change in women of different BMI categories. The MEDLINE, EMBASE, LILACS, and CINAHL databases were searched (1990-August 2019). Observational studies on interpregnancy BMI change were selected. Outcomes evaluated were gestational diabetes mellitus (GDM), preeclampsia, gestational hypertension (GH), cesarean section, preterm birth, and newborns being large (LGA) or small (SGA) for gestational age. Meta-analyses and meta-regression analyses were executed. Thirty studies were included (n > 1 million). Interpregnancy BMI gain was associated with a higher risk of GDM (for BMI gain >= 3 kg/m(2): OR 2.21; [95%CI 1.53-3.19]), preeclampsia (1.77 [1.53-2.04]), GH (1.78 [1.61-1.97]), cesarean section (1.32 [1.24-1.39]), and LGA (1.54 [1.28-1.86]). The effects of BMI gain were most pronounced in women with BMI

Original language	English
Article number	12974
Number of pages	10
Journal	Obesity Reviews
Volume	21
Issue number	3
DOIs	https://doi.org/10.1111/obr.12974
Publication status	Published - Mar 2020

Keywords

body mass index
cesarean delivery
gestational diabetes
obesity
pregnancy
BODY-MASS INDEX
PREGNANCY OUTCOMES
MATERNAL OBESITY
PRETERM BIRTH
BMI CHANGE
RISK
2ND-PREGNANCY
PREECLAMPSIA
ASSOCIATION
CATEGORIES

Access to Document

10.1111/obr.12974Licence: CC BY-NC-ND

Cite this

@article{be5fbb7855124973b0aa69c81f039b97,

title = "The impact of interpregnancy weight change on perinatal outcomes in women and their children: A systematic review and meta-analysis",

abstract = "Prepregnancy overweight and obesity are associated with higher risk of perinatal complications. However, the effect of weight change prior to pregnancy on perinatal outcome is largely unknown. Therefore, it is aimed to examine the impact on perinatal outcomes of interpregnancy BMI change in women of different BMI categories. The MEDLINE, EMBASE, LILACS, and CINAHL databases were searched (1990-August 2019). Observational studies on interpregnancy BMI change were selected. Outcomes evaluated were gestational diabetes mellitus (GDM), preeclampsia, gestational hypertension (GH), cesarean section, preterm birth, and newborns being large (LGA) or small (SGA) for gestational age. Meta-analyses and meta-regression analyses were executed. Thirty studies were included (n > 1 million). Interpregnancy BMI gain was associated with a higher risk of GDM (for BMI gain >= 3 kg/m(2): OR 2.21; [95%CI 1.53-3.19]), preeclampsia (1.77 [1.53-2.04]), GH (1.78 [1.61-1.97]), cesarean section (1.32 [1.24-1.39]), and LGA (1.54 [1.28-1.86]). The effects of BMI gain were most pronounced in women with BMI",

keywords = "body mass index, cesarean delivery, gestational diabetes, obesity, pregnancy, BODY-MASS INDEX, PREGNANCY OUTCOMES, MATERNAL OBESITY, PRETERM BIRTH, BMI CHANGE, RISK, 2ND-PREGNANCY, PREECLAMPSIA, ASSOCIATION, CATEGORIES",

author = "Timmermans, {Yvon E. G.} and {van de Kant}, {Kim D. G.} and Oosterman, {Elise O.} and Spaanderman, {Marc E. A.} and Eduardo Villamor-Martinez and Jos Kleijnen and Vreugdenhil, {Anita C. E.}",

note = "Funding Information: We gratefully acknowledge Steven Duffy (Kleijnen Systematic Reviews [KSR] Ltd, York, UK) for checking the search strategy. No funding sources were available for this work. Publisher Copyright: {\textcopyright} 2019 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation",

year = "2020",

month = mar,

doi = "10.1111/obr.12974",

language = "English",

volume = "21",

journal = "Obesity Reviews",

issn = "1467-7881",

publisher = "Wiley-Blackwell",

number = "3",

}

TY - JOUR

T1 - The impact of interpregnancy weight change on perinatal outcomes in women and their children

T2 - A systematic review and meta-analysis

AU - Timmermans, Yvon E. G.

AU - van de Kant, Kim D. G.

AU - Oosterman, Elise O.

AU - Spaanderman, Marc E. A.

AU - Villamor-Martinez, Eduardo

AU - Kleijnen, Jos

AU - Vreugdenhil, Anita C. E.

N1 - Funding Information: We gratefully acknowledge Steven Duffy (Kleijnen Systematic Reviews [KSR] Ltd, York, UK) for checking the search strategy. No funding sources were available for this work. Publisher Copyright: © 2019 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation

PY - 2020/3

Y1 - 2020/3

N2 - Prepregnancy overweight and obesity are associated with higher risk of perinatal complications. However, the effect of weight change prior to pregnancy on perinatal outcome is largely unknown. Therefore, it is aimed to examine the impact on perinatal outcomes of interpregnancy BMI change in women of different BMI categories. The MEDLINE, EMBASE, LILACS, and CINAHL databases were searched (1990-August 2019). Observational studies on interpregnancy BMI change were selected. Outcomes evaluated were gestational diabetes mellitus (GDM), preeclampsia, gestational hypertension (GH), cesarean section, preterm birth, and newborns being large (LGA) or small (SGA) for gestational age. Meta-analyses and meta-regression analyses were executed. Thirty studies were included (n > 1 million). Interpregnancy BMI gain was associated with a higher risk of GDM (for BMI gain >= 3 kg/m(2): OR 2.21; [95%CI 1.53-3.19]), preeclampsia (1.77 [1.53-2.04]), GH (1.78 [1.61-1.97]), cesarean section (1.32 [1.24-1.39]), and LGA (1.54 [1.28-1.86]). The effects of BMI gain were most pronounced in women with BMI

AB - Prepregnancy overweight and obesity are associated with higher risk of perinatal complications. However, the effect of weight change prior to pregnancy on perinatal outcome is largely unknown. Therefore, it is aimed to examine the impact on perinatal outcomes of interpregnancy BMI change in women of different BMI categories. The MEDLINE, EMBASE, LILACS, and CINAHL databases were searched (1990-August 2019). Observational studies on interpregnancy BMI change were selected. Outcomes evaluated were gestational diabetes mellitus (GDM), preeclampsia, gestational hypertension (GH), cesarean section, preterm birth, and newborns being large (LGA) or small (SGA) for gestational age. Meta-analyses and meta-regression analyses were executed. Thirty studies were included (n > 1 million). Interpregnancy BMI gain was associated with a higher risk of GDM (for BMI gain >= 3 kg/m(2): OR 2.21; [95%CI 1.53-3.19]), preeclampsia (1.77 [1.53-2.04]), GH (1.78 [1.61-1.97]), cesarean section (1.32 [1.24-1.39]), and LGA (1.54 [1.28-1.86]). The effects of BMI gain were most pronounced in women with BMI

KW - body mass index

KW - cesarean delivery

KW - gestational diabetes

KW - obesity

KW - pregnancy

KW - BODY-MASS INDEX

KW - PREGNANCY OUTCOMES

KW - MATERNAL OBESITY

KW - PRETERM BIRTH

KW - BMI CHANGE

KW - RISK

KW - 2ND-PREGNANCY

KW - PREECLAMPSIA

KW - ASSOCIATION

KW - CATEGORIES

U2 - 10.1111/obr.12974

DO - 10.1111/obr.12974

M3 - (Systematic) Review article

C2 - 31751496

SN - 1467-7881

VL - 21

JO - Obesity Reviews

JF - Obesity Reviews

IS - 3

M1 - 12974

ER -

The impact of interpregnancy weight change on perinatal outcomes in women and their children: A systematic review and meta-analysis

Abstract

Keywords

Access to Document

Fingerprint

Cite this