TY - JOUR
T1 - The impact of genetics and genomics on public health
AU - Brand, Angela
AU - Brand, Helmut
AU - Schulte in den Bäumen, Tobias
N1 - Funding Information:
This paper is an updated version of a presentation at the symposium entitled ‘Fascinated with Genetics’ on the occasion of the 65th birthday of Professor Leo ten Kate in Amsterdam, The Netherlands, on 17 March 2005. I (A Brand) thank Professor Leo ten Kate, pioneer of community genetics in Europe, and Professor Martina Cornel for inviting her to this outstanding symposium and for asking me to develop my thoughts on the intersection of genomics and public health. This paper is a result of the work of the Public Health Genomics European Network (PHGEN), which is funded in the Public Health Programme of the European Commission (project number 2005313).
PY - 2008/1
Y1 - 2008/1
N2 - Public health practice has to date concerned itself with environmental or social determinants of health and disease and has paid scant attention to genomic variations within the population. The advances brought about by genomics are changing these perceptions. In the long run, this knowledge will enable health promotion messages and disease prevention programmes to be specifically directed at susceptible individuals and families, or at subgroups of the population, based on their genomic risk profile. As the controversial discourse in science and health politics shows, the integration of genomics into public health research, policy and practice is one of the major challenges that our health-care system is currently facing.
AB - Public health practice has to date concerned itself with environmental or social determinants of health and disease and has paid scant attention to genomic variations within the population. The advances brought about by genomics are changing these perceptions. In the long run, this knowledge will enable health promotion messages and disease prevention programmes to be specifically directed at susceptible individuals and families, or at subgroups of the population, based on their genomic risk profile. As the controversial discourse in science and health politics shows, the integration of genomics into public health research, policy and practice is one of the major challenges that our health-care system is currently facing.
U2 - 10.1038/sj.ejhg.5201942
DO - 10.1038/sj.ejhg.5201942
M3 - (Systematic) Review article
C2 - 17957226
AN - SCOPUS:37249001740
SN - 1018-4813
VL - 16
SP - 5
EP - 13
JO - European Journal of Human Genetics
JF - European Journal of Human Genetics
IS - 1
ER -