The efficacy and safety of a nicotine conjugate vaccine (NicVAX (R)) or placebo co-administered with varenicline (Champix (R)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

Philippe H. J. Hoogsteder; Daniel Kotz; Paul I. van Spiegel; Wolfgang Viechtbauer; Ruth Brauer; Paul D. Kessler; Matthew W. Kalnik; Raafat E. F. Fahim; Onno C. P. van Schayck

doi:10.1186/1471-2458-12-1052

The efficacy and safety of a nicotine conjugate vaccine (NicVAX (R)) or placebo co-administered with varenicline (Champix (R)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

Philippe H. J. Hoogsteder^*, Daniel Kotz, Paul I. van Spiegel, Wolfgang Viechtbauer, Ruth Brauer, Paul D. Kessler, Matthew W. Kalnik, Raafat E. F. Fahim, Onno C. P. van Schayck

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1052
Journal	BMC Public Health
Volume	12
DOIs	https://doi.org/10.1186/1471-2458-12-1052
Publication status	Published - 6 Dec 2012

Keywords

Nicotine vaccination
NicVAX
Varenicline
Combination therapy
Efficacy
Safety
Immunogenicity
Randomized controlled trial

Access to Document

10.1186/1471-2458-12-1052Licence: CC BY

Cite this

Hoogsteder, P. H. J., Kotz, D., van Spiegel, P. I., Viechtbauer, W., Brauer, R., Kessler, P. D., Kalnik, M. W., Fahim, R. E. F., & van Schayck, O. C. P. (2012). The efficacy and safety of a nicotine conjugate vaccine (NicVAX (R)) or placebo co-administered with varenicline (Champix (R)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial. BMC Public Health, 12, 1052. https://doi.org/10.1186/1471-2458-12-1052

Hoogsteder, Philippe H. J. ; Kotz, Daniel ; van Spiegel, Paul I. ; Viechtbauer, Wolfgang ; Brauer, Ruth ; Kessler, Paul D. ; Kalnik, Matthew W. ; Fahim, Raafat E. F. ; van Schayck, Onno C. P. / The efficacy and safety of a nicotine conjugate vaccine (NicVAX (R)) or placebo co-administered with varenicline (Champix (R)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial. In: BMC Public Health. 2012 ; Vol. 12. pp. 1052.

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keywords = "Nicotine vaccination, NicVAX, Varenicline, Combination therapy, Efficacy, Safety, Immunogenicity, Randomized controlled trial",

author = "Hoogsteder, {Philippe H. J.} and Daniel Kotz and {van Spiegel}, {Paul I.} and Wolfgang Viechtbauer and Ruth Brauer and Kessler, {Paul D.} and Kalnik, {Matthew W.} and Fahim, {Raafat E. F.} and {van Schayck}, {Onno C. P.}",

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doi = "10.1186/1471-2458-12-1052",

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Hoogsteder, PHJ, Kotz, D, van Spiegel, PI, Viechtbauer, W, Brauer, R, Kessler, PD, Kalnik, MW, Fahim, REF & van Schayck, OCP 2012, 'The efficacy and safety of a nicotine conjugate vaccine (NicVAX (R)) or placebo co-administered with varenicline (Champix (R)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial', BMC Public Health, vol. 12, pp. 1052. https://doi.org/10.1186/1471-2458-12-1052

The efficacy and safety of a nicotine conjugate vaccine (NicVAX (R)) or placebo co-administered with varenicline (Champix (R)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial. / Hoogsteder, Philippe H. J.; Kotz, Daniel; van Spiegel, Paul I.; Viechtbauer, Wolfgang; Brauer, Ruth; Kessler, Paul D.; Kalnik, Matthew W.; Fahim, Raafat E. F.; van Schayck, Onno C. P.

In: BMC Public Health, Vol. 12, 06.12.2012, p. 1052.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Viechtbauer, Wolfgang

AU - Brauer, Ruth

AU - Kessler, Paul D.

AU - Kalnik, Matthew W.

AU - Fahim, Raafat E. F.

AU - van Schayck, Onno C. P.

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KW - Combination therapy

KW - Efficacy

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Hoogsteder PHJ, Kotz D, van Spiegel PI, Viechtbauer W, Brauer R, Kessler PD et al. The efficacy and safety of a nicotine conjugate vaccine (NicVAX (R)) or placebo co-administered with varenicline (Champix (R)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial. BMC Public Health. 2012 Dec 6;12:1052. https://doi.org/10.1186/1471-2458-12-1052