The efficacy and safety of a nicotine conjugate vaccine (NicVAX (R)) or placebo co-administered with varenicline (Champix (R)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

Philippe H. J. Hoogsteder*, Daniel Kotz, Paul I. van Spiegel, Wolfgang Viechtbauer, Ruth Brauer, Paul D. Kessler, Matthew W. Kalnik, Raafat E. F. Fahim, Onno C. P. van Schayck

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1052
JournalBMC Public Health
Publication statusPublished - 6 Dec 2012


  • Nicotine vaccination
  • NicVAX
  • Varenicline
  • Combination therapy
  • Efficacy
  • Safety
  • Immunogenicity
  • Randomized controlled trial

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