TY - JOUR
T1 - The effects of once- versus twice-weekly sessions on psychotherapy outcomes in depressed patients
AU - Bruijniks, Sanne J E
AU - Lemmens, Lotte H.J.M.
AU - Hollon, Steven D
AU - Peeters, Frenk P.M.L.
AU - Cuijpers, Pim
AU - Arntz, Arnoud
AU - Dingemanse, Pieter
AU - Willems, Linda
AU - van Oppen, Patricia
AU - Twisk, Jos W R
AU - van den Boogaard, Michael
AU - Spijker, Jan
AU - Bosmans, Judith
AU - Huibers, Marcus J.H.
N1 - Funding Information:
This study was funded by ZonMw and Stichting tot Steun VCVGZ. The funders were not involved in the study design; the collection, analysis and interpretation of data; the writing of the report or the decision to submit the article for publication.
Publisher Copyright:
© Copyright The Authors 2020.
PY - 2020/4
Y1 - 2020/4
N2 - BACKGROUND: It is unclear what session frequency is most effective in cognitive-behavioural therapy (CBT) and interpersonal psychotherapy (IPT) for depression.AIMS: Compare the effects of once weekly and twice weekly sessions of CBT and IPT for depression.METHOD: We conducted a multicentre randomised trial from November 2014 through December 2017. We recruited 200 adults with depression across nine specialised mental health centres in the Netherlands. This study used a 2 × 2 factorial design, randomising patients to once or twice weekly sessions of CBT or IPT over 16-24 weeks, up to a maximum of 20 sessions. Main outcome measures were depression severity, measured with the Beck Depression Inventory-II at baseline, before session 1, and 2 weeks, 1, 2, 3, 4, 5 and 6 months after start of the intervention. Intention-to-treat analyses were conducted.RESULTS: Compared with patients who received weekly sessions, patients who received twice weekly sessions showed a statistically significant decrease in depressive symptoms (estimated mean difference between weekly and twice weekly sessions at month 6: 3.85 points, difference in effect size d = 0.55), lower attrition rates (n = 16 compared with n = 32) and an increased rate of response (hazard ratio 1.48, 95% CI 1.00-2.18).CONCLUSIONS: In clinical practice settings, delivery of twice weekly sessions of CBT and IPT for depression is a way to improve depression treatment outcomes.
AB - BACKGROUND: It is unclear what session frequency is most effective in cognitive-behavioural therapy (CBT) and interpersonal psychotherapy (IPT) for depression.AIMS: Compare the effects of once weekly and twice weekly sessions of CBT and IPT for depression.METHOD: We conducted a multicentre randomised trial from November 2014 through December 2017. We recruited 200 adults with depression across nine specialised mental health centres in the Netherlands. This study used a 2 × 2 factorial design, randomising patients to once or twice weekly sessions of CBT or IPT over 16-24 weeks, up to a maximum of 20 sessions. Main outcome measures were depression severity, measured with the Beck Depression Inventory-II at baseline, before session 1, and 2 weeks, 1, 2, 3, 4, 5 and 6 months after start of the intervention. Intention-to-treat analyses were conducted.RESULTS: Compared with patients who received weekly sessions, patients who received twice weekly sessions showed a statistically significant decrease in depressive symptoms (estimated mean difference between weekly and twice weekly sessions at month 6: 3.85 points, difference in effect size d = 0.55), lower attrition rates (n = 16 compared with n = 32) and an increased rate of response (hazard ratio 1.48, 95% CI 1.00-2.18).CONCLUSIONS: In clinical practice settings, delivery of twice weekly sessions of CBT and IPT for depression is a way to improve depression treatment outcomes.
KW - COGNITIVE-BEHAVIORAL THERAPY
KW - DISORDER
KW - Depressive disorders
KW - INTERPERSONAL PSYCHOTHERAPY
KW - INVENTORY
KW - PSYCHOMETRIC PROPERTIES
KW - RANDOMIZED CONTROLLED-TRIAL
KW - STANDARD
KW - cognitive-behavioural therapies
KW - individual psychotherapy
KW - out-patient treatment
KW - randomised controlled trial
U2 - 10.1192/bjp.2019.265
DO - 10.1192/bjp.2019.265
M3 - Article
C2 - 32029012
SN - 0007-1250
VL - 216
SP - 222
EP - 230
JO - British Journal of Psychiatry
JF - British Journal of Psychiatry
IS - 4
ER -