The Effects of High- Versus Moderate-Intensity Exercise on Fatigue in Sarcoidosis

Anita Grongstad*, Nina K. Vollestad, Line M. Oldervoll, Martijn A. Spruit, Anne Edvardsen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: Fatigue is a common symptom in patients with sarcoidosis. Despite lacking evidence on whether high-intensity interval training (HIIT) will aggravate fatigue, moderate-intensity exercise is often recommended. This study aimed to investigate whether a single session of HIIT would affect fatigue differently from a single session of moderate-intensity continuous training (MICT). Methods: Forty-one patients with pulmonary sarcoidosis were recruited to a cross-over study. All patients completed one treadmill session of HIIT (85% of peak heart rate (HRpeak)) and one of MICT (70% of HRpeak). Fatigue was assessed with the Visual Analogue Scale 0-100 mm, before (T0), after (T1), and 24 hours after (T2) each exercise session. Paired sample t-test was used to compare changes in fatigue from T0 to T1 and from T0 to T2 between HIIT and MICT. Results: No statistically significant difference in fatigue levels was found between HIIT and MICT, either at T1 (3.6 (13.5) and 1.4 (13.5)) or at T2 (8.2 (17.0) and 2.1 (17.1)). Conclusions: A single session of HIIT did not affect fatigue differently than a single session of MICT. These preliminary findings support the need for further research on the long-term effect of HIIT on fatigue in patients with sarcoidosis.

Original languageEnglish
Article number460
Pages (from-to)1-11
Number of pages11
JournalJournal of Clinical Medicine
Volume8
Issue number4
DOIs
Publication statusPublished - Apr 2019

Keywords

  • pulmonary sarcoidosis
  • endurance training
  • high-intensity interval training
  • feasibility
  • INTERVAL
  • QUALITY
  • SCALE
  • INTOLERANCE
  • ADAPTATIONS
  • STATEMENT
  • CAPACITY
  • SUPERIOR
  • BENEFITS
  • FITNESS

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