The Effect of Rate Control on Quality of Life in Patients With Permanent Atrial Fibrillation Data From the RACE II (Rate Control Efficacy in Permanent Atrial Fibrillation II) Study

Hessel F. Groenveld, Harry J. G. M. Crijns, Maarten P. Van den Berg, Eric Van Sonderen, A. Marco Alings, Jan G. P. Tijssen, Hans L. Hillege, Ype S. Tuininga, Dirk J. van Veldhuisen, Adelita V. Ranchor, Isabelle C. Van Gelder*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Objectives The aim of this study was to investigate the influence of rate control on quality of life (QOL). Background The RACE II (Rate Control Efficacy in Permanent Atrial Fibrillation II) trial showed that lenient rate control is not inferior to strict rate control in terms of cardiovascular morbidity and mortality. The influence of stringency of rate control on QOL is unknown. Methods In RACE II, a total of 614 patients with permanent atrial fibrillation (AF) were randomized to lenient (resting heart rate [HR]
Original languageEnglish
Pages (from-to)1795-1803
JournalJournal of the American College of Cardiology
Issue number17
Publication statusPublished - 18 Oct 2011


  • atrial fibrillation
  • quality of life
  • rate control

Cite this