The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment

M.L. Tolhuisen; J. Enthoven; E.M.M. Santos; W.J. Niessen; L.F.M. Beenen; D.W.J. Dippel; A. van der Lugt; W.H. van Zwam; Y.B.W.E.M. Roos; R.J. van Oostenbrugge; C.B.L.M. Majoie; H.A. Marquering

doi:10.1007/978-3-319-67564-0_17

The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment

M.L. Tolhuisen^*, J. Enthoven, E.M.M. Santos, W.J. Niessen, L.F.M. Beenen, D.W.J. Dippel, A. van der Lugt, W.H. van Zwam, Y.B.W.E.M. Roos, R.J. van Oostenbrugge, C.B.L.M. Majoie, H.A. Marquering

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceeding › Academic › peer-review

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Abstract

Background] It is expected that thrombus density and perviousness measurements are dependent on CT slice thickness, because density values are blurred in thicker slices. This study quantifies the effect of slice thickness on thrombus density and perviousness measurements. [Methods] Thrombus density and perviousness measurements were performed in 50 patients for varying slice thicknesses, using a manual and semi-automated technique. Linear regression was performed to determine the dependence of density measurements on slice thickness. Paired t-tests were used to test for differences in density and perviousness measures for varying slice thickness. [Results] Thrombus density decreased for increasing slice thickness with approximately 2HU per mm. Perviousness measurements were significantly higher for thick slice compared to thin slice NCCT. [Conclusion] Thick slice NCCT scans result in an underestimation of thrombus density and overestimation of thrombus perviousness.

Original language	English
Title of host publication	MOLECULAR IMAGING, RECONSTRUCTION AND ANALYSIS OF MOVING BODY ORGANS, AND STROKE IMAGING AND TREATMENT
Editors	M. Jorge Cardoso, Tal Arbel
Publisher	Springer International Publishing AG
Pages	168-175
Number of pages	8
Edition	1
ISBN (Print)	9783319675633
DOIs	https://doi.org/10.1007/978-3-319-67564-0_17
Publication status	Published - 2017
Event	1st Int Workshop on Computat Methods for Mol Imaging (CMMI) / 2nd Int Workshop on Reconstruct & Analysis of Moving Body Organs (RAMBO) / 1st Int Stroke Workshop on Imaging & Treatment Challenges (SWITCH) - , Canada Duration: 10 Sept 2017 → 10 Sept 2017

Publication series

Series	Lecture Notes in Computer Science
Volume	10555
ISSN	0302-9743

Conference

Conference	1st Int Workshop on Computat Methods for Mol Imaging (CMMI) / 2nd Int Workshop on Reconstruct & Analysis of Moving Body Organs (RAMBO) / 1st Int Stroke Workshop on Imaging & Treatment Challenges (SWITCH)
Country/Territory	Canada
Period	10/09/17 → 10/09/17

Keywords

Ischemic stroke
Thrombus density
Thrombus perviousness
CT
Slice thickness

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10.1007/978-3-319-67564-0_17

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Tolhuisen, M. L., Enthoven, J., Santos, E. M. M., Niessen, W. J., Beenen, L. F. M., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Majoie, C. B. L. M., & Marquering, H. A. (2017). The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment. In M. J. Cardoso, & T. Arbel (Eds.), MOLECULAR IMAGING, RECONSTRUCTION AND ANALYSIS OF MOVING BODY ORGANS, AND STROKE IMAGING AND TREATMENT (1 ed., pp. 168-175). Springer International Publishing AG. https://doi.org/10.1007/978-3-319-67564-0_17

Tolhuisen, M.L. ; Enthoven, J. ; Santos, E.M.M. et al. / The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment. MOLECULAR IMAGING, RECONSTRUCTION AND ANALYSIS OF MOVING BODY ORGANS, AND STROKE IMAGING AND TREATMENT. editor / M. Jorge Cardoso ; Tal Arbel. 1. ed. Springer International Publishing AG, 2017. pp. 168-175 (Lecture Notes in Computer Science, Vol. 10555).

@inproceedings{05c4ce2073464fe3942ddc68399fafdf,

title = "The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment",

abstract = "Background] It is expected that thrombus density and perviousness measurements are dependent on CT slice thickness, because density values are blurred in thicker slices. This study quantifies the effect of slice thickness on thrombus density and perviousness measurements. [Methods] Thrombus density and perviousness measurements were performed in 50 patients for varying slice thicknesses, using a manual and semi-automated technique. Linear regression was performed to determine the dependence of density measurements on slice thickness. Paired t-tests were used to test for differences in density and perviousness measures for varying slice thickness. [Results] Thrombus density decreased for increasing slice thickness with approximately 2HU per mm. Perviousness measurements were significantly higher for thick slice compared to thin slice NCCT. [Conclusion] Thick slice NCCT scans result in an underestimation of thrombus density and overestimation of thrombus perviousness.",

keywords = "Ischemic stroke, Thrombus density, Thrombus perviousness, CT, Slice thickness",

author = "M.L. Tolhuisen and J. Enthoven and E.M.M. Santos and W.J. Niessen and L.F.M. Beenen and D.W.J. Dippel and {van der Lugt}, A. and {van Zwam}, W.H. and Y.B.W.E.M. Roos and {van Oostenbrugge}, R.J. and C.B.L.M. Majoie and H.A. Marquering",

year = "2017",

doi = "10.1007/978-3-319-67564-0_17",

language = "English",

isbn = "9783319675633",

series = "Lecture Notes in Computer Science",

publisher = "Springer International Publishing AG",

pages = "168--175",

editor = "Cardoso, {M. Jorge} and Tal Arbel",

booktitle = "MOLECULAR IMAGING, RECONSTRUCTION AND ANALYSIS OF MOVING BODY ORGANS, AND STROKE IMAGING AND TREATMENT",

edition = "1",

note = "1st Int Workshop on Computat Methods for Mol Imaging (CMMI) / 2nd Int Workshop on Reconstruct & Analysis of Moving Body Organs (RAMBO) / 1st Int Stroke Workshop on Imaging & Treatment Challenges (SWITCH) ; Conference date: 10-09-2017 Through 10-09-2017",

}

Tolhuisen, ML, Enthoven, J, Santos, EMM, Niessen, WJ, Beenen, LFM, Dippel, DWJ, van der Lugt, A, van Zwam, WH, Roos, YBWEM, van Oostenbrugge, RJ, Majoie, CBLM & Marquering, HA 2017, The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment. in MJ Cardoso & T Arbel (eds), MOLECULAR IMAGING, RECONSTRUCTION AND ANALYSIS OF MOVING BODY ORGANS, AND STROKE IMAGING AND TREATMENT. 1 edn, Springer International Publishing AG, Lecture Notes in Computer Science, vol. 10555, pp. 168-175, 1st Int Workshop on Computat Methods for Mol Imaging (CMMI) / 2nd Int Workshop on Reconstruct & Analysis of Moving Body Organs (RAMBO) / 1st Int Stroke Workshop on Imaging & Treatment Challenges (SWITCH), Canada, 10/09/17. https://doi.org/10.1007/978-3-319-67564-0_17

The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment. / Tolhuisen, M.L.; Enthoven, J.; Santos, E.M.M. et al.
MOLECULAR IMAGING, RECONSTRUCTION AND ANALYSIS OF MOVING BODY ORGANS, AND STROKE IMAGING AND TREATMENT. ed. / M. Jorge Cardoso; Tal Arbel. 1. ed. Springer International Publishing AG, 2017. p. 168-175 (Lecture Notes in Computer Science, Vol. 10555).

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceeding › Academic › peer-review

TY - GEN

T1 - The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment

AU - Tolhuisen, M.L.

AU - Enthoven, J.

AU - Santos, E.M.M.

AU - Niessen, W.J.

AU - Beenen, L.F.M.

AU - Dippel, D.W.J.

AU - van der Lugt, A.

AU - van Zwam, W.H.

AU - Roos, Y.B.W.E.M.

AU - van Oostenbrugge, R.J.

AU - Majoie, C.B.L.M.

AU - Marquering, H.A.

PY - 2017

Y1 - 2017

N2 - Background] It is expected that thrombus density and perviousness measurements are dependent on CT slice thickness, because density values are blurred in thicker slices. This study quantifies the effect of slice thickness on thrombus density and perviousness measurements. [Methods] Thrombus density and perviousness measurements were performed in 50 patients for varying slice thicknesses, using a manual and semi-automated technique. Linear regression was performed to determine the dependence of density measurements on slice thickness. Paired t-tests were used to test for differences in density and perviousness measures for varying slice thickness. [Results] Thrombus density decreased for increasing slice thickness with approximately 2HU per mm. Perviousness measurements were significantly higher for thick slice compared to thin slice NCCT. [Conclusion] Thick slice NCCT scans result in an underestimation of thrombus density and overestimation of thrombus perviousness.

AB - Background] It is expected that thrombus density and perviousness measurements are dependent on CT slice thickness, because density values are blurred in thicker slices. This study quantifies the effect of slice thickness on thrombus density and perviousness measurements. [Methods] Thrombus density and perviousness measurements were performed in 50 patients for varying slice thicknesses, using a manual and semi-automated technique. Linear regression was performed to determine the dependence of density measurements on slice thickness. Paired t-tests were used to test for differences in density and perviousness measures for varying slice thickness. [Results] Thrombus density decreased for increasing slice thickness with approximately 2HU per mm. Perviousness measurements were significantly higher for thick slice compared to thin slice NCCT. [Conclusion] Thick slice NCCT scans result in an underestimation of thrombus density and overestimation of thrombus perviousness.

KW - Ischemic stroke

KW - Thrombus density

KW - Thrombus perviousness

KW - CT

KW - Slice thickness

U2 - 10.1007/978-3-319-67564-0_17

DO - 10.1007/978-3-319-67564-0_17

M3 - Conference article in proceeding

SN - 9783319675633

T3 - Lecture Notes in Computer Science

SP - 168

EP - 175

BT - MOLECULAR IMAGING, RECONSTRUCTION AND ANALYSIS OF MOVING BODY ORGANS, AND STROKE IMAGING AND TREATMENT

A2 - Cardoso, M. Jorge

A2 - Arbel, Tal

PB - Springer International Publishing AG

T2 - 1st Int Workshop on Computat Methods for Mol Imaging (CMMI) / 2nd Int Workshop on Reconstruct & Analysis of Moving Body Organs (RAMBO) / 1st Int Stroke Workshop on Imaging & Treatment Challenges (SWITCH)

Y2 - 10 September 2017 through 10 September 2017

ER -

Tolhuisen ML, Enthoven J, Santos EMM, Niessen WJ, Beenen LFM, Dippel DWJ et al. The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment. In Cardoso MJ, Arbel T, editors, MOLECULAR IMAGING, RECONSTRUCTION AND ANALYSIS OF MOVING BODY ORGANS, AND STROKE IMAGING AND TREATMENT. 1 ed. Springer International Publishing AG. 2017. p. 168-175. (Lecture Notes in Computer Science, Vol. 10555). doi: 10.1007/978-3-319-67564-0_17

The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment

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