THE EFFECT OF ITPA POLYMORPHISMS ON THE ENZYME KINETIC PROPERTIES OF HUMAN ERYTHROCYTE INOSINE TRIPHOSPHATASE TOWARD ITS SUBSTRATES ITP AND 6-THIO-ITP

Jaap A. Bakker, Martijn Lindhout, Daphna D. J. Habets, Arthur van den Wijngaard, Aimee D. C. Paulussen, Jorgen Bierau

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)839-849
JournalNucleosides Nucleotides & Nucleic Acids
Volume30
Issue number11
DOIs
Publication statusPublished - 2011

Keywords

  • ITPase
  • thiopurines
  • adverse drug reactions
  • substrate specificity
  • pharmacogenetics

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