Abstract
Department of Human Biology, University of Maastricht, Maastricht, The Netherlands. M.Westerterp@HB.Unimaas.nl
OBJECTIVE: Assessment of the effects of 2 weeks of daily administration of HCA on energy intake and satiety in overweight men and women. DESIGN: A 6-week randomized placebo-controlled single-blinded cross-over trial. SUBJECTS: consumed three times daily for 2 weeks 100 ml tomato juice (placebo) and, separated by a 2 week wash-out period, 100 ml tomato juice with 300 mg HCA.Subjects: Twelve males and 12 females (body mass index 27.5+/-2.0 kg/m(2); age 37+/-10 y). MEASUREMENTS: After 2 weeks, 24 h energy intake (EI), appetite profile, hedonics, mood and possible change in dietary restraint were assessed in the laboratory restaurant. Prevention of degradation and bio-availability was documented.RESULTS: Twenty-four-hour EI was decreased by 15-30% (P<0.05) with HCA treatment compared to placebo, without changes in the appetite profile, dietary restraint, mood, taste perception and hedonics, while body weight tended to decrease (P=0.1).CONCLUSION: HCA treatment reduced 24 h EI in humans while satiety was sustained.
Publication Types:
Clinical Trial
Randomized Controlled Trial
OBJECTIVE: Assessment of the effects of 2 weeks of daily administration of HCA on energy intake and satiety in overweight men and women. DESIGN: A 6-week randomized placebo-controlled single-blinded cross-over trial. SUBJECTS: consumed three times daily for 2 weeks 100 ml tomato juice (placebo) and, separated by a 2 week wash-out period, 100 ml tomato juice with 300 mg HCA.Subjects: Twelve males and 12 females (body mass index 27.5+/-2.0 kg/m(2); age 37+/-10 y). MEASUREMENTS: After 2 weeks, 24 h energy intake (EI), appetite profile, hedonics, mood and possible change in dietary restraint were assessed in the laboratory restaurant. Prevention of degradation and bio-availability was documented.RESULTS: Twenty-four-hour EI was decreased by 15-30% (P<0.05) with HCA treatment compared to placebo, without changes in the appetite profile, dietary restraint, mood, taste perception and hedonics, while body weight tended to decrease (P=0.1).CONCLUSION: HCA treatment reduced 24 h EI in humans while satiety was sustained.
Publication Types:
Clinical Trial
Randomized Controlled Trial
| Original language | English |
|---|---|
| Pages (from-to) | 870-872 |
| Number of pages | 3 |
| Journal | International Journal of Obesity |
| Volume | 26 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1 Jan 2002 |