The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033

Pierre Bady, Sebastian Kurscheid, Mauro Delorenzi, Thierry Gorlia, Martin J. van den Bent, Khe Hoang-Xuan, Elodie Vauleon, Anja Gijtenbeek, Roelien Enting, Brian Thiessen, Olivier Chinot, Frederic Dhermain, Alba A. Brandes, Jaap C. Reijneveld, Christine Marosi, Martin J. B. Taphoorn, Wolfgang Wick, Andreas von Deimling, Pim French, Roger StuppBrigitta G. Baumert, Monika E. Hegi

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)601-615
Number of pages15
JournalActa Neuropathologica
Volume135
Issue number4
DOIs
Publication statusPublished - 1 Apr 2018

Keywords

  • Low-grade glioma
  • DNA methylation
  • TMZ
  • DDR genes
  • MGMT-STP27
  • Randomized trial
  • MISMATCH REPAIR
  • METHYLATION
  • GLIOBLASTOMA
  • EXPRESSION
  • MGMT
  • TEMOZOLOMIDE
  • TUMORS
  • CELLS
  • RADIOTHERAPY
  • SENSITIVITY

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