TY - JOUR
T1 - The Determinants of Quality of Life of Nursing Home Residents with Young-Onset Dementia and the Differences between Dementia Subtypes
AU - Appelhof, Britt
AU - Bakker, Christian
AU - Van Duinen-van den Ijssel, Jeannette C. L.
AU - Zwijsen, Sandra A.
AU - Smalbrugge, Martin
AU - Verhey, Frans R. J.
AU - de Vugt, Marjolein E.
AU - Zuidema, Sytse U.
AU - Koopnnans, Raymond T. C. M.
PY - 2017
Y1 - 2017
N2 - Aims: The aims of this study are to (1) explore the determinants of quality of life (QoL) in nursing home residents with young-onset dementia (YOD), (2) investigate whether there are differences between dementia subtypes (Alzheimer dementia, vascular/mixed dementia, frontotemporal dementia, other) regarding these determinants, and (3) compare QoL profiles of YOD nursing home residents across dementia subtypes. Methods: This cross-sectional study included 207 nursing home residents. Multilevel modeling was used to determine the relationships between QoL and neuropsychiatric symptoms (NPS), dementia severity, psychotropic drug use (PDU), dementia subtype, age, and gender. Additional multilevel models were used to compare aspects of QoL between dementia subtypes. Results: Residents' QoL was negatively associated with advanced dementia, PDU, and NPS. In general, the relationships between the determinants and QoL were similar across the dementia subtypes. Aspects of QoL differed by dementia subtype. Residents with frontotemporal dementia showed less negative emotions, accepted more help and experienced better quality of relationships with professional caregivers, had a more positive self-image, felt more comfortable in the nursing home environment, and experienced lower quality of social relationships. Conclusions: Considering the high rates of NPS and PDU in YOD residents and their negative associations with QoL, we recommend emphasizing services to manage and reduce NPS and PDU in nursing home residents with YOD. Furthermore, our findings suggest accounting for differences in aspects of QoL by dementia subtype to address specific needs and thereby improve QoL. (C) 2017 The Author(s) Published by S. Karger AG, Basel
AB - Aims: The aims of this study are to (1) explore the determinants of quality of life (QoL) in nursing home residents with young-onset dementia (YOD), (2) investigate whether there are differences between dementia subtypes (Alzheimer dementia, vascular/mixed dementia, frontotemporal dementia, other) regarding these determinants, and (3) compare QoL profiles of YOD nursing home residents across dementia subtypes. Methods: This cross-sectional study included 207 nursing home residents. Multilevel modeling was used to determine the relationships between QoL and neuropsychiatric symptoms (NPS), dementia severity, psychotropic drug use (PDU), dementia subtype, age, and gender. Additional multilevel models were used to compare aspects of QoL between dementia subtypes. Results: Residents' QoL was negatively associated with advanced dementia, PDU, and NPS. In general, the relationships between the determinants and QoL were similar across the dementia subtypes. Aspects of QoL differed by dementia subtype. Residents with frontotemporal dementia showed less negative emotions, accepted more help and experienced better quality of relationships with professional caregivers, had a more positive self-image, felt more comfortable in the nursing home environment, and experienced lower quality of social relationships. Conclusions: Considering the high rates of NPS and PDU in YOD residents and their negative associations with QoL, we recommend emphasizing services to manage and reduce NPS and PDU in nursing home residents with YOD. Furthermore, our findings suggest accounting for differences in aspects of QoL by dementia subtype to address specific needs and thereby improve QoL. (C) 2017 The Author(s) Published by S. Karger AG, Basel
KW - Young-onset dementia
KW - Quality of life
KW - Nursing home
KW - Neuropsychiatric symptoms
KW - Psychotropic drugs
KW - LONG-TERM-CARE
KW - ALZHEIMERS-DISEASE
KW - FRONTOTEMPORAL DEMENTIA
KW - NEUROPSYCHIATRIC INVENTORY
KW - PSYCHOLOGICAL SYMPTOMS
KW - DIAGNOSTIC-CRITERIA
KW - CAREGIVERS
KW - FACILITIES
KW - PEOPLE
KW - VALIDATION
U2 - 10.1159/000477087
DO - 10.1159/000477087
M3 - Article
C2 - 28558375
SN - 1420-8008
VL - 43
SP - 320
EP - 329
JO - Dementia and Geriatric Cognitive Disorders
JF - Dementia and Geriatric Cognitive Disorders
IS - 5-6
ER -