The capacity of mid-pregnancy cervical length to predict preterm birth in low-risk women: a national cohort study

Jeanine van der Ven*, Melanie A. van Os, Brenda M. Kazemier, Emily Kleinrouweler, Corine J. Verhoeven, Esteriek de Miranda, Aleid G. van Wassenaer-Leemhuis, Petra N. Kuiper, Martina Porath, Christine Willekes, Mallory D. Woiski, Marko J. Sikkema, Frans J. M. E. Roumen, Patrick M. Bossuyt, Monique C. Haak, Christianne J. M. de Groot, Ben W. J. Mol, Eva Pajkrt

*Corresponding author for this work

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Introduction We investigated the predictive capacity of mid-trimester cervical length (CL) measurement for spontaneous and iatrogenic preterm birth. Material and methodsWe performed a prospective observational cohort study in nulliparous women and low-risk multiparous women with a singleton pregnancy between 16(+0) and 21(+6)weeks of gestation. We assessed the prognostic capacity of transvaginally measured mid-trimester CL for spontaneous and iatrogenic preterm birth (
Original languageEnglish
Pages (from-to)1223-1234
JournalActa Obstetricia et Gynecologica Scandinavica
Issue number11
Publication statusPublished - Nov 2015


  • Cervical length measurement
  • preterm birth
  • low-risk population

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