The C-terminus of tissue factor pathway inhibitor-alpha inhibits factor V activation by protecting the Arg(1545) cleavage site

P. van Doorn, J. Rosing, S. J. Wielders, T. M. Hackeng, E. Castoldi*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)140-149
Number of pages10
JournalJournal of Thrombosis and Haemostasis
Volume15
Issue number1
DOIs
Publication statusPublished - Jan 2017

Keywords

  • factor V
  • factor Xa
  • prothrombinase complex
  • thrombin
  • tissue factor pathway inhibitor
  • THROMBIN-CATALYZED ACTIVATION
  • TEXAS BLEEDING DISORDER
  • B-DOMAIN
  • FACTOR-XA
  • ANTICOAGULANT ACTIVITY
  • PROTEIN-C
  • COAGULATION
  • TFPI
  • PROTHROMBINASE
  • RELEASE

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