The bidirectional interaction between atrial fibrillation and heart failure: consequences for the management of both diseases

Dominique V. M. Verhaert*, Hans-Peter Brunner-La Rocca, Dirk J. van Veldhuisen, Kevin Vernooy

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Web of Science)

Abstract

Atrial fibrillation (AF) and heart failure (HF) are both highly prevalent diseases and are accompanied by a significant disease burden and increased mortality. Although the conditions may exist independently, they often go hand in hand as each is able to provoke, sustain, and aggravate the other. In addition, the diseases share a risk profile with several coinciding cardiovascular risk factors, promoting the odds of developing both AF and HF separately from each other. When the diseases coexist, this provides additional challenges but also opportunities for the optimal treatment. The recommended management of the comorbidities has been much debated in the past decades. In this review, we describe the pathophysiological coherence of AF and HF, illustrate the current knowledge on the management of them as comorbidities of each other and look forward to future developments in this field.

Original languageEnglish
Pages (from-to)40-45
Number of pages6
JournalEP Europace
Volume23
DOIs
Publication statusPublished - Apr 2021

Keywords

  • Atrial fibrillation
  • Heart failure
  • Tachycardiomyopathy
  • Pathophysiology
  • HFrEF
  • HFpEF
  • Treatment
  • Catheter ablation
  • Pulmonary vein isolation
  • CATHETER ABLATION
  • SYSTOLIC DYSFUNCTION
  • RHYTHM CONTROL
  • TACHYCARDIA
  • BURDEN
  • TRIAL

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