The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults

Anouk M. M. Vaes; Elske M. Brouwer-Brolsma; Nicole Toussaint; Margot de Regt; Michael Tieland; Luc J. C. van Loon; Lisette C. P. G. M. de Groot

doi:10.1007/s00394-018-1634-0

The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults

Anouk M. M. Vaes^*, Elske M. Brouwer-Brolsma, Nicole Toussaint, Margot de Regt, Michael Tieland, Luc J. C. van Loon, Lisette C. P. G. M. de Groot

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

PurposeSufficient 25-hydroxyvitamin D (25(OH)D) concentrations might prevent a decline in physical performance, and are considered important for the prevention of frailty. This study investigates the association of serum 25(OH)D concentration with physical performance and frailty status in Dutch older adults.MethodsThis cross-sectional study included 756 men and women, aged65years. Serum 25(OH)D concentration and frailty status (Fried criteria) were assessed in the total population. Screening for frailty status included functional tests of gait speed and hand grip strength. In a subgroup (n=494), the Timed Up and Go test (TUG) and knee-extension strength were measured. Associations of serum 25(OH)D status with physical performance were examined by multiple linear regression. Prevalence ratios (PR) were used to quantify associations between serum 25(OH)D deficiency (75nmol/L. No significant associations with serum 25(OH)D concentrations were observed for handgrip strength or knee-extension strength. Participants with serum 25(OH)D status

Original language	English
Pages (from-to)	1173-1181
Number of pages	9
Journal	European Journal of Nutrition
Volume	58
Issue number	3
DOIs	https://doi.org/10.1007/s00394-018-1634-0
Publication status	Published - Apr 2019

Keywords

25-Hydroxyvitamin D
Vitamin D
Muscle strength
Physical performance
Frailty
VITAMIN-D LEVELS
MUSCLE STRENGTH
MEN
HEALTH
MORTALITY
CALCIUM
FALLS

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Cite this

@article{ac1c73a34f184402b8e13397f8533336,

title = "The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults",

abstract = "PurposeSufficient 25-hydroxyvitamin D (25(OH)D) concentrations might prevent a decline in physical performance, and are considered important for the prevention of frailty. This study investigates the association of serum 25(OH)D concentration with physical performance and frailty status in Dutch older adults.MethodsThis cross-sectional study included 756 men and women, aged65years. Serum 25(OH)D concentration and frailty status (Fried criteria) were assessed in the total population. Screening for frailty status included functional tests of gait speed and hand grip strength. In a subgroup (n=494), the Timed Up and Go test (TUG) and knee-extension strength were measured. Associations of serum 25(OH)D status with physical performance were examined by multiple linear regression. Prevalence ratios (PR) were used to quantify associations between serum 25(OH)D deficiency (75nmol/L. No significant associations with serum 25(OH)D concentrations were observed for handgrip strength or knee-extension strength. Participants with serum 25(OH)D status",

keywords = "25-Hydroxyvitamin D, Vitamin D, Muscle strength, Physical performance, Frailty, VITAMIN-D LEVELS, MUSCLE STRENGTH, MEN, HEALTH, MORTALITY, CALCIUM, FALLS",

author = "Vaes, {Anouk M. M.} and Brouwer-Brolsma, {Elske M.} and Nicole Toussaint and {de Regt}, Margot and Michael Tieland and {van Loon}, {Luc J. C.} and {de Groot}, {Lisette C. P. G. M.}",

note = "Publisher Copyright: {\textcopyright} 2018, The Author(s).",

year = "2019",

month = apr,

doi = "10.1007/s00394-018-1634-0",

language = "English",

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T1 - The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults

AU - Vaes, Anouk M. M.

AU - Brouwer-Brolsma, Elske M.

AU - Toussaint, Nicole

AU - de Regt, Margot

AU - Tieland, Michael

AU - van Loon, Luc J. C.

AU - de Groot, Lisette C. P. G. M.

PY - 2019/4

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N2 - PurposeSufficient 25-hydroxyvitamin D (25(OH)D) concentrations might prevent a decline in physical performance, and are considered important for the prevention of frailty. This study investigates the association of serum 25(OH)D concentration with physical performance and frailty status in Dutch older adults.MethodsThis cross-sectional study included 756 men and women, aged65years. Serum 25(OH)D concentration and frailty status (Fried criteria) were assessed in the total population. Screening for frailty status included functional tests of gait speed and hand grip strength. In a subgroup (n=494), the Timed Up and Go test (TUG) and knee-extension strength were measured. Associations of serum 25(OH)D status with physical performance were examined by multiple linear regression. Prevalence ratios (PR) were used to quantify associations between serum 25(OH)D deficiency (75nmol/L. No significant associations with serum 25(OH)D concentrations were observed for handgrip strength or knee-extension strength. Participants with serum 25(OH)D status

AB - PurposeSufficient 25-hydroxyvitamin D (25(OH)D) concentrations might prevent a decline in physical performance, and are considered important for the prevention of frailty. This study investigates the association of serum 25(OH)D concentration with physical performance and frailty status in Dutch older adults.MethodsThis cross-sectional study included 756 men and women, aged65years. Serum 25(OH)D concentration and frailty status (Fried criteria) were assessed in the total population. Screening for frailty status included functional tests of gait speed and hand grip strength. In a subgroup (n=494), the Timed Up and Go test (TUG) and knee-extension strength were measured. Associations of serum 25(OH)D status with physical performance were examined by multiple linear regression. Prevalence ratios (PR) were used to quantify associations between serum 25(OH)D deficiency (75nmol/L. No significant associations with serum 25(OH)D concentrations were observed for handgrip strength or knee-extension strength. Participants with serum 25(OH)D status

KW - 25-Hydroxyvitamin D

KW - Vitamin D

KW - Muscle strength

KW - Physical performance

KW - Frailty

KW - VITAMIN-D LEVELS

KW - MUSCLE STRENGTH

KW - MEN

KW - HEALTH

KW - MORTALITY

KW - CALCIUM

KW - FALLS

U2 - 10.1007/s00394-018-1634-0

DO - 10.1007/s00394-018-1634-0

M3 - Article

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SN - 1436-6207

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JO - European Journal of Nutrition

JF - European Journal of Nutrition

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