The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults

Anouk M. M. Vaes*, Elske M. Brouwer-Brolsma, Nicole Toussaint, Margot de Regt, Michael Tieland, Luc J. C. van Loon, Lisette C. P. G. M. de Groot

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Web of Science)

Abstract

PurposeSufficient 25-hydroxyvitamin D (25(OH)D) concentrations might prevent a decline in physical performance, and are considered important for the prevention of frailty. This study investigates the association of serum 25(OH)D concentration with physical performance and frailty status in Dutch older adults.MethodsThis cross-sectional study included 756 men and women, aged65years. Serum 25(OH)D concentration and frailty status (Fried criteria) were assessed in the total population. Screening for frailty status included functional tests of gait speed and hand grip strength. In a subgroup (n=494), the Timed Up and Go test (TUG) and knee-extension strength were measured. Associations of serum 25(OH)D status with physical performance were examined by multiple linear regression. Prevalence ratios (PR) were used to quantify associations between serum 25(OH)D deficiency (75nmol/L. No significant associations with serum 25(OH)D concentrations were observed for handgrip strength or knee-extension strength. Participants with serum 25(OH)D status

Original languageEnglish
Pages (from-to)1173-1181
Number of pages9
JournalEuropean Journal of Nutrition
Volume58
Issue number3
DOIs
Publication statusPublished - Apr 2019

Keywords

  • 25-Hydroxyvitamin D
  • Vitamin D
  • Muscle strength
  • Physical performance
  • Frailty
  • VITAMIN-D LEVELS
  • MUSCLE STRENGTH
  • MEN
  • HEALTH
  • MORTALITY
  • CALCIUM
  • FALLS

Cite this