The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect

Sanne W. ten Broeke; Mar Rodriguez-Girondo; Manon Suerink; Stefan Aretz; Inge Bernstein; Gabriel Capella; Christoph Engel; Encarna B. Gomez-Garcia; Liselot P. van Hest; Magnus von Knebel Doeberitz; Kristina Lagerstedt-Robinson; Tom G. W. Letteboer; Pal Moller; Theo A. van Os; Marta Pineda; Nils Rahner; Maran J. W. Olderode-Berends; Jenny von Salome; Hans K. Schackert; Liesbeth Spruijt; Verena Steinke-Lange; Anja Wagner; Carli M. J. Tops; Maartje Nielsen

doi:10.1158/1055-9965.EPI-18-0576

The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect

Sanne W. ten Broeke^*, Mar Rodriguez-Girondo, Manon Suerink, Stefan Aretz, Inge Bernstein, Gabriel Capella, Christoph Engel, Encarna B. Gomez-Garcia, Liselot P. van Hest, Magnus von Knebel Doeberitz, Kristina Lagerstedt-Robinson, Tom G. W. Letteboer, Pal Moller, Theo A. van Os, Marta Pineda, Nils Rahner, Maran J. W. Olderode-Berends, Jenny von Salome, Hans K. Schackert, Liesbeth SpruijtVerena Steinke-Lange, Anja Wagner, Carli M. J. Tops, Maartje Nielsen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1010-1014
Number of pages	5
Journal	Cancer Epidemiology Biomarkers & Prevention
Volume	28
Issue number	6
DOIs	https://doi.org/10.1158/1055-9965.EPI-18-0576
Publication status	Published - Jun 2019

Keywords

COLORECTAL-CANCER
NO EVIDENCE
HETEROGENEITY
RISK

Access to Document

10.1158/1055-9965.EPI-18-0576

Cite this

ten Broeke, S. W., Rodriguez-Girondo, M., Suerink, M., Aretz, S., Bernstein, I., Capella, G., Engel, C., Gomez-Garcia, E. B., van Hest, L. P., Doeberitz, M. V. K., Lagerstedt-Robinson, K., Letteboer, T. G. W., Moller, P., van Os, T. A., Pineda, M., Rahner, N., Olderode-Berends, M. J. W., von Salome, J., Schackert, H. K., ... Nielsen, M. (2019). The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect. Cancer Epidemiology Biomarkers & Prevention, 28(6), 1010-1014. https://doi.org/10.1158/1055-9965.EPI-18-0576

ten Broeke, Sanne W. ; Rodriguez-Girondo, Mar ; Suerink, Manon ; Aretz, Stefan ; Bernstein, Inge ; Capella, Gabriel ; Engel, Christoph ; Gomez-Garcia, Encarna B. ; van Hest, Liselot P. ; Doeberitz, Magnus von Knebel ; Lagerstedt-Robinson, Kristina ; Letteboer, Tom G. W. ; Moller, Pal ; van Os, Theo A. ; Pineda, Marta ; Rahner, Nils ; Olderode-Berends, Maran J. W. ; von Salome, Jenny ; Schackert, Hans K. ; Spruijt, Liesbeth ; Steinke-Lange, Verena ; Wagner, Anja ; Tops, Carli M. J. ; Nielsen, Maartje. / The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect. In: Cancer Epidemiology Biomarkers & Prevention. 2019 ; Vol. 28, No. 6. pp. 1010-1014.

@article{0160d1bedce74b1890139e35eb97f792,

title = "The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect",

keywords = "COLORECTAL-CANCER, NO EVIDENCE, HETEROGENEITY, RISK",

author = "{ten Broeke}, {Sanne W.} and Mar Rodriguez-Girondo and Manon Suerink and Stefan Aretz and Inge Bernstein and Gabriel Capella and Christoph Engel and Gomez-Garcia, {Encarna B.} and {van Hest}, {Liselot P.} and Doeberitz, {Magnus von Knebel} and Kristina Lagerstedt-Robinson and Letteboer, {Tom G. W.} and Pal Moller and {van Os}, {Theo A.} and Marta Pineda and Nils Rahner and Olderode-Berends, {Maran J. W.} and {von Salome}, Jenny and Schackert, {Hans K.} and Liesbeth Spruijt and Verena Steinke-Lange and Anja Wagner and Tops, {Carli M. J.} and Maartje Nielsen",

year = "2019",

month = jun,

doi = "10.1158/1055-9965.EPI-18-0576",

language = "English",

volume = "28",

pages = "1010--1014",

journal = "Cancer Epidemiology Biomarkers & Prevention",

issn = "1055-9965",

publisher = "American Association for Cancer Research Inc.",

number = "6",

}

ten Broeke, SW, Rodriguez-Girondo, M, Suerink, M, Aretz, S, Bernstein, I, Capella, G, Engel, C, Gomez-Garcia, EB, van Hest, LP, Doeberitz, MVK, Lagerstedt-Robinson, K, Letteboer, TGW, Moller, P, van Os, TA, Pineda, M, Rahner, N, Olderode-Berends, MJW, von Salome, J, Schackert, HK, Spruijt, L, Steinke-Lange, V, Wagner, A, Tops, CMJ & Nielsen, M 2019, 'The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect', Cancer Epidemiology Biomarkers & Prevention, vol. 28, no. 6, pp. 1010-1014. https://doi.org/10.1158/1055-9965.EPI-18-0576

The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect. / ten Broeke, Sanne W.; Rodriguez-Girondo, Mar; Suerink, Manon; Aretz, Stefan; Bernstein, Inge; Capella, Gabriel; Engel, Christoph; Gomez-Garcia, Encarna B.; van Hest, Liselot P.; Doeberitz, Magnus von Knebel; Lagerstedt-Robinson, Kristina; Letteboer, Tom G. W.; Moller, Pal; van Os, Theo A.; Pineda, Marta; Rahner, Nils; Olderode-Berends, Maran J. W.; von Salome, Jenny; Schackert, Hans K.; Spruijt, Liesbeth; Steinke-Lange, Verena; Wagner, Anja; Tops, Carli M. J.; Nielsen, Maartje.

In: Cancer Epidemiology Biomarkers & Prevention, Vol. 28, No. 6, 06.2019, p. 1010-1014.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect

AU - ten Broeke, Sanne W.

AU - Rodriguez-Girondo, Mar

AU - Suerink, Manon

AU - Aretz, Stefan

AU - Bernstein, Inge

AU - Capella, Gabriel

AU - Engel, Christoph

AU - Gomez-Garcia, Encarna B.

AU - van Hest, Liselot P.

AU - Doeberitz, Magnus von Knebel

AU - Lagerstedt-Robinson, Kristina

AU - Letteboer, Tom G. W.

AU - Moller, Pal

AU - van Os, Theo A.

AU - Pineda, Marta

AU - Rahner, Nils

AU - Olderode-Berends, Maran J. W.

AU - von Salome, Jenny

AU - Schackert, Hans K.

AU - Spruijt, Liesbeth

AU - Steinke-Lange, Verena

AU - Wagner, Anja

AU - Tops, Carli M. J.

AU - Nielsen, Maartje

PY - 2019/6

Y1 - 2019/6

KW - COLORECTAL-CANCER

KW - NO EVIDENCE

KW - HETEROGENEITY

KW - RISK

U2 - 10.1158/1055-9965.EPI-18-0576

DO - 10.1158/1055-9965.EPI-18-0576

M3 - Article

C2 - 30824524

VL - 28

SP - 1010

EP - 1014

JO - Cancer Epidemiology Biomarkers & Prevention

JF - Cancer Epidemiology Biomarkers & Prevention

SN - 1055-9965

IS - 6

ER -