The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion

Mandy M. F. Steinbusch, Marjolein M. J. Caron, Don A. M. Surtel, Guus G. H. van den Akker, Paul J. van Dijk, Franziska Friedrich, Bernhard Zabel, Lodewijk W. van Rhijn, Mandy J. Peffers, Tim J. M. Welting*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)5121-5136
Number of pages16
JournalJournal of Biological Chemistry
Volume294
Issue number13
DOIs
Publication statusPublished - 29 Mar 2019

Keywords

  • cartilage biology
  • chondrogenesis
  • small nucleolar RNA (snoRNA)
  • transforming growth factor beta (TGF-B)
  • chemokine
  • secretion
  • C-X-C motif chemokine ligand 10
  • cartilage-hair hypoplasia
  • chondrogenic differentiation
  • RMRP snoRNA
  • viperin
  • INTERFERON-INDUCIBLE PROTEIN
  • MESENCHYMAL STEM-CELLS
  • RNASE MRP
  • GENE-EXPRESSION
  • MESSENGER-RNA
  • GROWTH-FACTOR
  • INHIBITION
  • GAMMA
  • ACTIVATION
  • MUTATIONS

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