The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro

Femke Verhees*, Dion Legemaate, Imke Demers, Robin Jacobs, Wisse Evert Haakma, Mat Rousch, Bernd Kremer, Ernst Jan Speel

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number919
Number of pages15
JournalCancers
Volume11
Issue number7
DOIs
Publication statusPublished - 26 Jun 2019

Keywords

  • human papillomavirus
  • head and neck cancer
  • double-stranded DNA breaks
  • DNA repair
  • cell line
  • cyclin B1
  • Aurora Kinase A
  • ACYCLIC NUCLEOSIDE PHOSPHONATES
  • HUMAN-PAPILLOMAVIRUS
  • LINES
  • RADIOSENSITIVITY
  • INHIBITOR
  • APOPTOSIS
  • SURVIVAL
  • GROWTH
  • REPAIR
  • DEATH

Cite this

@article{92792a47b2044eee880e3709c799cb9d,
title = "The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro",
keywords = "human papillomavirus, head and neck cancer, double-stranded DNA breaks, DNA repair, cell line, cyclin B1, Aurora Kinase A, ACYCLIC NUCLEOSIDE PHOSPHONATES, HUMAN-PAPILLOMAVIRUS, LINES, RADIOSENSITIVITY, INHIBITOR, APOPTOSIS, SURVIVAL, GROWTH, REPAIR, DEATH",
author = "Femke Verhees and Dion Legemaate and Imke Demers and Robin Jacobs and Haakma, {Wisse Evert} and Mat Rousch and Bernd Kremer and Speel, {Ernst Jan}",
year = "2019",
month = "6",
day = "26",
doi = "10.3390/cancers11070919",
language = "English",
volume = "11",
journal = "Cancers",
issn = "2072-6694",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "7",

}

The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro. / Verhees, Femke; Legemaate, Dion; Demers, Imke; Jacobs, Robin; Haakma, Wisse Evert; Rousch, Mat; Kremer, Bernd; Speel, Ernst Jan.

In: Cancers, Vol. 11, No. 7, 919, 26.06.2019.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro

AU - Verhees, Femke

AU - Legemaate, Dion

AU - Demers, Imke

AU - Jacobs, Robin

AU - Haakma, Wisse Evert

AU - Rousch, Mat

AU - Kremer, Bernd

AU - Speel, Ernst Jan

PY - 2019/6/26

Y1 - 2019/6/26

KW - human papillomavirus

KW - head and neck cancer

KW - double-stranded DNA breaks

KW - DNA repair

KW - cell line

KW - cyclin B1

KW - Aurora Kinase A

KW - ACYCLIC NUCLEOSIDE PHOSPHONATES

KW - HUMAN-PAPILLOMAVIRUS

KW - LINES

KW - RADIOSENSITIVITY

KW - INHIBITOR

KW - APOPTOSIS

KW - SURVIVAL

KW - GROWTH

KW - REPAIR

KW - DEATH

U2 - 10.3390/cancers11070919

DO - 10.3390/cancers11070919

M3 - Article

VL - 11

JO - Cancers

JF - Cancers

SN - 2072-6694

IS - 7

M1 - 919

ER -