The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro

Femke Verhees*, Dion Legemaate, Imke Demers, Robin Jacobs, Wisse Evert Haakma, Mat Rousch, Bernd Kremer, Ernst Jan Speel

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number919
Number of pages15
JournalCancers
Volume11
Issue number7
DOIs
Publication statusPublished - 26 Jun 2019

Keywords

  • human papillomavirus
  • head and neck cancer
  • double-stranded DNA breaks
  • DNA repair
  • cell line
  • cyclin B1
  • Aurora Kinase A
  • ACYCLIC NUCLEOSIDE PHOSPHONATES
  • HUMAN-PAPILLOMAVIRUS
  • LINES
  • RADIOSENSITIVITY
  • INHIBITOR
  • APOPTOSIS
  • SURVIVAL
  • GROWTH
  • REPAIR
  • DEATH

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