Keyphrases
Antimalarial Drugs
100%
T Cells
100%
T-cell Acute Lymphoblastic Leukemia (T-ALL)
100%
Chloroquine
100%
Notch1
100%
Secretase
100%
γ-secretase Inhibitor
66%
Cell Viability
22%
Acute Lymphoblastic Leukemia Cells
22%
Chemotherapy
11%
Cell Proliferation
11%
New Treatment Options
11%
Current Treatment
11%
Aggressive Tumor
11%
Autophagosome
11%
Clinical Efficacy
11%
Clinical Dose
11%
Dose-limiting Toxicity
11%
Single Treatment
11%
Improved Survival
11%
Therapeutic Ratio
11%
Redox Balance
11%
Leukemia Cell Lines
11%
Single-stranded DNA (ssDNA)
11%
DNA Damage Response
11%
Drug Repurposing
11%
Small Molecule Inhibitors
11%
Fatal Infection
11%
Notch1 Signaling
11%
DNA Breaks
11%
γ-Secretase Inhibition
11%
Lysosomal Function
11%
Intracellular Trafficking
11%
NOTCH1 mutation
11%
Synergistic Therapeutic Effect
11%
Intracellular Processing
11%
Synergize
11%
Early T-cell Precursor
11%
Medicine and Dentistry
Carcinogenesis
100%
Chloroquine
100%
Acute Lymphoblastic Leukemia
100%
Secretase
100%
Antimalarial Agent
100%
Gamma Secretase Inhibitor
66%
Cell Viability
22%
Malignant Neoplasm
11%
Cell Proliferation
11%
Therapy Effect
11%
Glucocorticoid
11%
Autophagy
11%
T Cell
11%
Therapeutic Window
11%
Double Stranded DNA
11%
Leukemia Cell Line
11%
Leukemia Cell
11%
Intracellular Trafficking
11%
DNA Damage Response
11%
Gamma Secretase
11%
Diseases
11%
Pharmacology, Toxicology and Pharmaceutical Science
Carcinogenesis
100%
Chloroquine
100%
Acute Lymphoblastic Leukemia
100%
Secretase
100%
Antimalarial Agent
100%
Gamma Secretase Inhibitor
66%
Cell Viability
22%
Malignant Neoplasm
11%
Double Stranded DNA
11%
Chemotherapy
11%
Glucocorticoid
11%
Therapeutic Effect
11%
Therapeutic Window
11%
Gamma Secretase
11%
Diseases
11%
INIS
humans
100%
drugs
100%
inhibition
100%
leukemia
100%
concentration
22%
viability
22%
proliferation
22%
diseases
11%
doses
11%
reduction
11%
cancer
11%
increasing
11%
dna
11%
toxicity
11%
mutations
11%
dna damages
11%
chemotherapy
11%
processing
11%
molecules
11%
balances
11%
notches
11%
blocking
11%
bears
11%
glucocorticoids
11%
Biochemistry, Genetics and Molecular Biology
Carcinogenesis
100%
T Cell
100%
Secretase
100%
Gamma Secretase
70%
Cell Viability
20%
Small Molecule
10%
Cell Proliferation
10%
Autophagy
10%
DNA Damage Response
10%
Intracellular Trafficking
10%
Glucocorticoid
10%