The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice

Sabine A. S. Langie*, Kerry M. Cameron, Gabriella Ficz, David Oxley, Bartlomiej Tomaszewski, Joanna P. Gorniak, Lou M. Maas, Roger W. L. Godschalk, Frederik J. van Schooten, Wolf Reik, Thomas von Zglinicki, John C. Mathers

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number75
Number of pages19
JournalGenes
Volume8
Issue number2
DOIs
Publication statusPublished - Feb 2017

Keywords

  • DNA methylation
  • epigenetics
  • base excision repair
  • ageing
  • brain
  • gene regulation
  • BASE EXCISION-REPAIR
  • ALZHEIMERS-DISEASE
  • TRANSCRIPTIONAL REGULATION
  • OXIDATIVE STRESS
  • TET ENZYMES
  • EPIGENETIC REGULATION
  • DIETARY RESTRICTION
  • NUCLEAR-DNA
  • MOUSE-BRAIN
  • CANCER

Cite this

Langie, S. A. S., Cameron, K. M., Ficz, G., Oxley, D., Tomaszewski, B., Gorniak, J. P., ... Mathers, J. C. (2017). The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice. Genes, 8(2), [75]. https://doi.org/10.3390/genes8020075
Langie, Sabine A. S. ; Cameron, Kerry M. ; Ficz, Gabriella ; Oxley, David ; Tomaszewski, Bartlomiej ; Gorniak, Joanna P. ; Maas, Lou M. ; Godschalk, Roger W. L. ; van Schooten, Frederik J. ; Reik, Wolf ; von Zglinicki, Thomas ; Mathers, John C. / The Ageing Brain : Effects on DNA Repair and DNA Methylation in Mice. In: Genes. 2017 ; Vol. 8, No. 2.
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keywords = "DNA methylation, epigenetics, base excision repair, ageing, brain, gene regulation, BASE EXCISION-REPAIR, ALZHEIMERS-DISEASE, TRANSCRIPTIONAL REGULATION, OXIDATIVE STRESS, TET ENZYMES, EPIGENETIC REGULATION, DIETARY RESTRICTION, NUCLEAR-DNA, MOUSE-BRAIN, CANCER",
author = "Langie, {Sabine A. S.} and Cameron, {Kerry M.} and Gabriella Ficz and David Oxley and Bartlomiej Tomaszewski and Gorniak, {Joanna P.} and Maas, {Lou M.} and Godschalk, {Roger W. L.} and {van Schooten}, {Frederik J.} and Wolf Reik and {von Zglinicki}, Thomas and Mathers, {John C.}",
year = "2017",
month = "2",
doi = "10.3390/genes8020075",
language = "English",
volume = "8",
journal = "Genes",
issn = "2073-4425",
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Langie, SAS, Cameron, KM, Ficz, G, Oxley, D, Tomaszewski, B, Gorniak, JP, Maas, LM, Godschalk, RWL, van Schooten, FJ, Reik, W, von Zglinicki, T & Mathers, JC 2017, 'The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice', Genes, vol. 8, no. 2, 75. https://doi.org/10.3390/genes8020075

The Ageing Brain : Effects on DNA Repair and DNA Methylation in Mice. / Langie, Sabine A. S.; Cameron, Kerry M.; Ficz, Gabriella; Oxley, David; Tomaszewski, Bartlomiej; Gorniak, Joanna P.; Maas, Lou M.; Godschalk, Roger W. L.; van Schooten, Frederik J.; Reik, Wolf; von Zglinicki, Thomas; Mathers, John C.

In: Genes, Vol. 8, No. 2, 75, 02.2017.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - The Ageing Brain

T2 - Effects on DNA Repair and DNA Methylation in Mice

AU - Langie, Sabine A. S.

AU - Cameron, Kerry M.

AU - Ficz, Gabriella

AU - Oxley, David

AU - Tomaszewski, Bartlomiej

AU - Gorniak, Joanna P.

AU - Maas, Lou M.

AU - Godschalk, Roger W. L.

AU - van Schooten, Frederik J.

AU - Reik, Wolf

AU - von Zglinicki, Thomas

AU - Mathers, John C.

PY - 2017/2

Y1 - 2017/2

KW - DNA methylation

KW - epigenetics

KW - base excision repair

KW - ageing

KW - brain

KW - gene regulation

KW - BASE EXCISION-REPAIR

KW - ALZHEIMERS-DISEASE

KW - TRANSCRIPTIONAL REGULATION

KW - OXIDATIVE STRESS

KW - TET ENZYMES

KW - EPIGENETIC REGULATION

KW - DIETARY RESTRICTION

KW - NUCLEAR-DNA

KW - MOUSE-BRAIN

KW - CANCER

U2 - 10.3390/genes8020075

DO - 10.3390/genes8020075

M3 - Article

VL - 8

JO - Genes

JF - Genes

SN - 2073-4425

IS - 2

M1 - 75

ER -

Langie SAS, Cameron KM, Ficz G, Oxley D, Tomaszewski B, Gorniak JP et al. The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice. Genes. 2017 Feb;8(2). 75. https://doi.org/10.3390/genes8020075