People with diabetes are at an increased risk of developing cardiovascular diseases. The aim of the studies described in this dissertation was to examine the role of advanced glycation endproducts (AGEs) in the development of cardiovascular diseases in people with and without diabetes. A clear, consistent relation was found between AGE accumulation in the skin and the extent of vascular damage. Therefore, a strong indication exists that AGEs are involved in the development of vascular damage in people with and without diabetes. This research project provides more insight into the mechanism underlying the relationship between diabetes and cardiovascular diseases. Hopefully, this information contributes to the development of new therapies to prevent and cure diabetes and subsequent vascular damage.
|Award date||7 Sep 2017|
|Place of Publication||Maastricht|
|Publication status||Published - 2017|
- cardiovascular diseases
- advanced glycation endproducts