Test of cure, retesting and extragenital testing practices for Chlamydia trachomatis and Neisseria gonorrhoeae among general practitioners in different socioeconomic status areas: A retrospective cohort study, 2011-2016

Julien N. A. P. Wijers*, Genevieve A. F. S. van Liere, Christian J. P. A. Hoebe, Jochen W. L. Cals, Petra F. G. Wolffs, Nicole H. T. M. Dukers-Muijrers

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Web of Science)

Abstract

Background For Chlamydia trachomatis (CT), a test of cure (TOC) within 3 similar to 5 weeks is not recommended. International guidelines differ in advising a Neisseria gonorrhoeae (NG) TOC. Retesting CT and NG positives within 3 similar to 12 months is recommended in international guidelines. We assessed TOC and retesting practices including extragenital testing in general practitioner (GP) practices located in different socioeconomic status (SES) areas to inform and optimize local test practices. Methods Laboratory data of 48 Dutch GP practices between January 2011 and July 2016 were used. Based on a patient's first positive CT or NG test, the proportion of TOC (< 3 months) and retests (3 similar to 12 months) were calculated. Patient-and GP-related factors were assessed using multivariate logistic regression analyses. Results For CT (n = 622), 20% had a TOC and 24% had a retest at the GP practice. GP practices in low SES areas were more likely to perform a CT TOC (OR: 1.8; 95% CI: 1.1 similar to 3.1). Younger patients (< 25 years) were more likely to have a CT TOC (OR: 1.6; 95% CI: 1.0 similar to 2.4). For CT (n = 622), 2.4% had a TOC and 6.1% had a retest at another STI care provider. For NG (n = 73), 25% had a TOC and 15% had a retest at the GP practice. For NG (n = 73), 2.7% had a TOC and 12.3% had a retest at another STI care provider. In only 0.3% of the consultations patients were tested on extragenital sites. Conclusion Almost 20% of the patients returned for a CT TOC, especially at GP practices in low SES areas. For NG, 1 out of 4 patients returned for a TOC. Retesting rates were low for both CT (24%) and NG (15%), (re) infections including extragenital infections may be missed. Efforts are required to focus TOC and increase retesting practices of GPs in order to improve CT/NG control.
Original languageEnglish
Article numbere0194351
Number of pages15
JournalPLOS ONE
Volume13
Issue number3
DOIs
Publication statusPublished - 14 Mar 2018

Keywords

  • EUROPEAN GUIDELINE
  • REINFECTION RATES
  • REPEAT INFECTION
  • SMS REMINDERS
  • MEN
  • MANAGEMENT
  • WOMEN
  • SEX
  • Chlamydia trachomatis/isolation & purification
  • Chlamydia Infections/diagnosis
  • General Practitioners
  • Humans
  • Logistic Models
  • Male
  • Neisseria gonorrhoeae/isolation & purification
  • Social Class
  • Practice Patterns, Physicians'
  • Netherlands
  • Female
  • Gonorrhea/diagnosis
  • Retrospective Studies
  • Early Diagnosis
  • Practice Guidelines as Topic

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