Temporal association of ventricular arrhythmias and respiratory events in heart failure patients with central sleep apnoea

Valentin Guenzler; Michael Arzt; Marjorie Grimm; Amelie Ebert; Florian Zeman; Dominik Linz; Holger Woehrle; Renaud Tamisier; Martin Cowie; Christoph Fisser

doi:10.1016/j.sleep.2024.04.002

Temporal association of ventricular arrhythmias and respiratory events in heart failure patients with central sleep apnoea

Valentin Guenzler^*, Michael Arzt, Marjorie Grimm, Amelie Ebert, Florian Zeman, Dominik Linz, Holger Woehrle, Renaud Tamisier, Martin Cowie, Christoph Fisser

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In contrast to obstructive sleep apnoea, the peak of sympathetic tone in central sleep apnoea occurs during the hyperventilation phase. To explore the temporal association of premature ventricular complex (PVC) burden in the context of the apnoea/hypopnoea-hyperpnoea cycle, the duration of apnoea/hypopnoea was defined as 100 %. We assessed the PVC burden throughout the apnoea/hypopnoea-hyperpnoea cycle during the periods of ±150 % in 50 % increments before and after the apnoea/hypopnoea phase. In this subanalysis of 54 SERVE-HF patients, PVC burden was 32 % higher in the late hyperventilation period (50–100 % after apnoea/hypopnoea) compared to the apnoea/hypopnoea phase.

Original language	English
Pages (from-to)	59-62
Number of pages	4
Journal	Sleep Medicine
Volume	118
DOIs	https://doi.org/10.1016/j.sleep.2024.04.002
Publication status	Published - 1 Jun 2024

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title = "Temporal association of ventricular arrhythmias and respiratory events in heart failure patients with central sleep apnoea",

abstract = "In contrast to obstructive sleep apnoea, the peak of sympathetic tone in central sleep apnoea occurs during the hyperventilation phase. To explore the temporal association of premature ventricular complex (PVC) burden in the context of the apnoea/hypopnoea-hyperpnoea cycle, the duration of apnoea/hypopnoea was defined as 100 %. We assessed the PVC burden throughout the apnoea/hypopnoea-hyperpnoea cycle during the periods of ±150 % in 50 % increments before and after the apnoea/hypopnoea phase. In this subanalysis of 54 SERVE-HF patients, PVC burden was 32 % higher in the late hyperventilation period (50–100 % after apnoea/hypopnoea) compared to the apnoea/hypopnoea phase.",

author = "Valentin Guenzler and Michael Arzt and Marjorie Grimm and Amelie Ebert and Florian Zeman and Dominik Linz and Holger Woehrle and Renaud Tamisier and Martin Cowie and Christoph Fisser",

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doi = "10.1016/j.sleep.2024.04.002",

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TY - JOUR

T1 - Temporal association of ventricular arrhythmias and respiratory events in heart failure patients with central sleep apnoea

AU - Guenzler, Valentin

AU - Arzt, Michael

AU - Grimm, Marjorie

AU - Ebert, Amelie

AU - Zeman, Florian

AU - Linz, Dominik

AU - Woehrle, Holger

AU - Tamisier, Renaud

AU - Cowie, Martin

AU - Fisser, Christoph

PY - 2024/6/1

Y1 - 2024/6/1

N2 - In contrast to obstructive sleep apnoea, the peak of sympathetic tone in central sleep apnoea occurs during the hyperventilation phase. To explore the temporal association of premature ventricular complex (PVC) burden in the context of the apnoea/hypopnoea-hyperpnoea cycle, the duration of apnoea/hypopnoea was defined as 100 %. We assessed the PVC burden throughout the apnoea/hypopnoea-hyperpnoea cycle during the periods of ±150 % in 50 % increments before and after the apnoea/hypopnoea phase. In this subanalysis of 54 SERVE-HF patients, PVC burden was 32 % higher in the late hyperventilation period (50–100 % after apnoea/hypopnoea) compared to the apnoea/hypopnoea phase.

AB - In contrast to obstructive sleep apnoea, the peak of sympathetic tone in central sleep apnoea occurs during the hyperventilation phase. To explore the temporal association of premature ventricular complex (PVC) burden in the context of the apnoea/hypopnoea-hyperpnoea cycle, the duration of apnoea/hypopnoea was defined as 100 %. We assessed the PVC burden throughout the apnoea/hypopnoea-hyperpnoea cycle during the periods of ±150 % in 50 % increments before and after the apnoea/hypopnoea phase. In this subanalysis of 54 SERVE-HF patients, PVC burden was 32 % higher in the late hyperventilation period (50–100 % after apnoea/hypopnoea) compared to the apnoea/hypopnoea phase.

U2 - 10.1016/j.sleep.2024.04.002

DO - 10.1016/j.sleep.2024.04.002

M3 - Article

SN - 1389-9457

VL - 118

SP - 59

EP - 62

JO - Sleep Medicine

JF - Sleep Medicine

ER -

Temporal association of ventricular arrhythmias and respiratory events in heart failure patients with central sleep apnoea

Abstract

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