Technical aspects of neurostimulation: Focus on equipment, electric field modeling, and stimulation protocols

D. C. W. Klooster; A. J. A. de Louw; A. P. Aldenkamp; R. M. H. Besseling; R. M. C. Mestrom; S. Carrette; S. Zinger; J. W. M. Bergmans; W. H. Mess; K. Vonck; E. Carrette; L. E. M. Breuer; A. Bernas; A. G. Tijhuis; P. Boon

doi:10.1016/j.neubiorev.2016.02.016

Technical aspects of neurostimulation: Focus on equipment, electric field modeling, and stimulation protocols

D. C. W. Klooster^*, A. J. A. de Louw, A. P. Aldenkamp, R. M. H. Besseling, R. M. C. Mestrom, S. Carrette, S. Zinger, J. W. M. Bergmans, W. H. Mess, K. Vonck, E. Carrette, L. E. M. Breuer, A. Bernas, A. G. Tijhuis, P. Boon

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Neuromodulation is a field of science, medicine, and bioengineering that encompasses implantable and non-implantable technologies for the purpose of improving quality of life and functioning of humans. Brain neuromodulation involves different neurostimulation techniques: transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), vagus nerve stimulation (VNS), and deep brain stimulation (DBS), which are being used both to study their effects on cognitive brain functions and to treat neuropsychiatric disorders. The mechanisms of action of neurostimulation remain incompletely understood. Insight into the technical basis of neurostimulation might be a first step towards a more profound understanding of these mechanisms, which might lead to improved clinical outcome and therapeutic potential. This review provides an overview of the technical basis of neurostimulation focusing on the equipment, the present understanding of induced electric fields, and the stimulation protocols. The review is written from a technical perspective aimed at supporting the use of neurostimulation in clinical practice.

Original language	English
Pages (from-to)	113-141
Journal	Neuroscience and Biobehavioral Reviews
Volume	65
DOIs	https://doi.org/10.1016/j.neubiorev.2016.02.016
Publication status	Published - Jun 2016

Keywords

Neurostimulation
Deep brain stimulation
Vagus nerve stimulation
Transcranial magnetic stimulation
Transcranial direct current stimulation
Electric field modeling
Stimulation parameters
Stimulation protocol
Stimulation equipment

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10.1016/j.neubiorev.2016.02.016

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Klooster, D. C. W., de Louw, A. J. A., Aldenkamp, A. P., Besseling, R. M. H., Mestrom, R. M. C., Carrette, S., Zinger, S., Bergmans, J. W. M., Mess, W. H., Vonck, K., Carrette, E., Breuer, L. E. M., Bernas, A., Tijhuis, A. G., & Boon, P. (2016). Technical aspects of neurostimulation: Focus on equipment, electric field modeling, and stimulation protocols. Neuroscience and Biobehavioral Reviews, 65, 113-141. https://doi.org/10.1016/j.neubiorev.2016.02.016

@article{a849894df52b48658f659264781d4d07,

title = "Technical aspects of neurostimulation: Focus on equipment, electric field modeling, and stimulation protocols",

abstract = "Neuromodulation is a field of science, medicine, and bioengineering that encompasses implantable and non-implantable technologies for the purpose of improving quality of life and functioning of humans. Brain neuromodulation involves different neurostimulation techniques: transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), vagus nerve stimulation (VNS), and deep brain stimulation (DBS), which are being used both to study their effects on cognitive brain functions and to treat neuropsychiatric disorders. The mechanisms of action of neurostimulation remain incompletely understood. Insight into the technical basis of neurostimulation might be a first step towards a more profound understanding of these mechanisms, which might lead to improved clinical outcome and therapeutic potential. This review provides an overview of the technical basis of neurostimulation focusing on the equipment, the present understanding of induced electric fields, and the stimulation protocols. The review is written from a technical perspective aimed at supporting the use of neurostimulation in clinical practice. ",

keywords = "Neurostimulation, Deep brain stimulation, Vagus nerve stimulation, Transcranial magnetic stimulation, Transcranial direct current stimulation, Electric field modeling, Stimulation parameters, Stimulation protocol, Stimulation equipment",

author = "Klooster, {D. C. W.} and {de Louw}, {A. J. A.} and Aldenkamp, {A. P.} and Besseling, {R. M. H.} and Mestrom, {R. M. C.} and S. Carrette and S. Zinger and Bergmans, {J. W. M.} and Mess, {W. H.} and K. Vonck and E. Carrette and Breuer, {L. E. M.} and A. Bernas and Tijhuis, {A. G.} and P. Boon",

year = "2016",

month = jun,

doi = "10.1016/j.neubiorev.2016.02.016",

language = "English",

volume = "65",

pages = "113--141",

journal = "Neuroscience and Biobehavioral Reviews",

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Klooster, DCW, de Louw, AJA, Aldenkamp, AP, Besseling, RMH, Mestrom, RMC, Carrette, S, Zinger, S, Bergmans, JWM, Mess, WH, Vonck, K, Carrette, E, Breuer, LEM, Bernas, A, Tijhuis, AG & Boon, P 2016, 'Technical aspects of neurostimulation: Focus on equipment, electric field modeling, and stimulation protocols', Neuroscience and Biobehavioral Reviews, vol. 65, pp. 113-141. https://doi.org/10.1016/j.neubiorev.2016.02.016

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AU - Klooster, D. C. W.

AU - de Louw, A. J. A.

AU - Aldenkamp, A. P.

AU - Besseling, R. M. H.

AU - Mestrom, R. M. C.

AU - Carrette, S.

AU - Zinger, S.

AU - Bergmans, J. W. M.

AU - Mess, W. H.

AU - Vonck, K.

AU - Carrette, E.

AU - Breuer, L. E. M.

AU - Bernas, A.

AU - Tijhuis, A. G.

AU - Boon, P.

PY - 2016/6

Y1 - 2016/6

N2 - Neuromodulation is a field of science, medicine, and bioengineering that encompasses implantable and non-implantable technologies for the purpose of improving quality of life and functioning of humans. Brain neuromodulation involves different neurostimulation techniques: transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), vagus nerve stimulation (VNS), and deep brain stimulation (DBS), which are being used both to study their effects on cognitive brain functions and to treat neuropsychiatric disorders. The mechanisms of action of neurostimulation remain incompletely understood. Insight into the technical basis of neurostimulation might be a first step towards a more profound understanding of these mechanisms, which might lead to improved clinical outcome and therapeutic potential. This review provides an overview of the technical basis of neurostimulation focusing on the equipment, the present understanding of induced electric fields, and the stimulation protocols. The review is written from a technical perspective aimed at supporting the use of neurostimulation in clinical practice.

AB - Neuromodulation is a field of science, medicine, and bioengineering that encompasses implantable and non-implantable technologies for the purpose of improving quality of life and functioning of humans. Brain neuromodulation involves different neurostimulation techniques: transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), vagus nerve stimulation (VNS), and deep brain stimulation (DBS), which are being used both to study their effects on cognitive brain functions and to treat neuropsychiatric disorders. The mechanisms of action of neurostimulation remain incompletely understood. Insight into the technical basis of neurostimulation might be a first step towards a more profound understanding of these mechanisms, which might lead to improved clinical outcome and therapeutic potential. This review provides an overview of the technical basis of neurostimulation focusing on the equipment, the present understanding of induced electric fields, and the stimulation protocols. The review is written from a technical perspective aimed at supporting the use of neurostimulation in clinical practice.

KW - Neurostimulation

KW - Deep brain stimulation

KW - Vagus nerve stimulation

KW - Transcranial magnetic stimulation

KW - Transcranial direct current stimulation

KW - Electric field modeling

KW - Stimulation parameters

KW - Stimulation protocol

KW - Stimulation equipment

U2 - 10.1016/j.neubiorev.2016.02.016

DO - 10.1016/j.neubiorev.2016.02.016

M3 - Article

C2 - 27021215

SN - 0149-7634

VL - 65

SP - 113

EP - 141

JO - Neuroscience and Biobehavioral Reviews

JF - Neuroscience and Biobehavioral Reviews

ER -

Technical aspects of neurostimulation: Focus on equipment, electric field modeling, and stimulation protocols

Abstract

Keywords

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