Targeting Pyruvate Kinase M2 and Lactate Dehydrogenase A Is an Effective Combination Strategy for the Treatment of Pancreatic Cancer

Goran Hamid Mohammad, Vessela Vassileva, Pilar Acedo, Steven W. M. Olde Damink, Massimo Malago, Dipok Kumar Dhar, Stephen P. Pereira*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number1372
Number of pages15
JournalCancers
Volume11
Issue number9
DOIs
Publication statusPublished - Sep 2019

Keywords

  • pancreatic cancer
  • pyruvate kinase M2
  • lactate dehydrogenase A
  • glycolytic enzymes
  • combination therapy
  • TUMOR-GROWTH
  • PKM2
  • INHIBITORS
  • HYPOXIA
  • CELLS
  • OVEREXPRESSION
  • GEMCITABINE
  • PROGRESSION
  • METABOLISM
  • EXPRESSION

Cite this