Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment

Melissa Schepers, Assia Tiane, Dean Paes, Selien Sanchez, Ben Rombaut, Elisabeth Piccart, Bart P. F. Rutten, Bert Brone, Niels Hellings, Jos Prickaerts, Tim Vanmierlo*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Article number1727
Pages (from-to)1-17
Number of pages17
JournalFrontiers in Immunology
Volume10
DOIs
Publication statusPublished - 24 Jul 2019

Keywords

  • multiple sclerosis
  • phosphodiesterase
  • neuroinflammation
  • CNS repair
  • remyelination
  • BLOOD-BRAIN-BARRIER
  • EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
  • CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES
  • DISEASE NEUROFIBRILLARY CHANGES
  • GUANYLATE-CYCLASE ACTIVITY
  • APP/PS1 TRANSGENIC MICE
  • PROTEIN-KINASE-A
  • R6/2 MOUSE MODEL
  • ALZHEIMERS-DISEASE
  • OXIDATIVE STRESS

Cite this

Schepers, Melissa ; Tiane, Assia ; Paes, Dean ; Sanchez, Selien ; Rombaut, Ben ; Piccart, Elisabeth ; Rutten, Bart P. F. ; Brone, Bert ; Hellings, Niels ; Prickaerts, Jos ; Vanmierlo, Tim. / Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment. In: Frontiers in Immunology. 2019 ; Vol. 10. pp. 1-17.
@article{951444fb035145efbb4710234325e674,
title = "Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment",
keywords = "multiple sclerosis, phosphodiesterase, neuroinflammation, CNS repair, remyelination, BLOOD-BRAIN-BARRIER, EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS, CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES, DISEASE NEUROFIBRILLARY CHANGES, GUANYLATE-CYCLASE ACTIVITY, APP/PS1 TRANSGENIC MICE, PROTEIN-KINASE-A, R6/2 MOUSE MODEL, ALZHEIMERS-DISEASE, OXIDATIVE STRESS",
author = "Melissa Schepers and Assia Tiane and Dean Paes and Selien Sanchez and Ben Rombaut and Elisabeth Piccart and Rutten, {Bart P. F.} and Bert Brone and Niels Hellings and Jos Prickaerts and Tim Vanmierlo",
year = "2019",
month = "7",
day = "24",
doi = "10.3389/fimmu.2019.01727",
language = "English",
volume = "10",
pages = "1--17",
journal = "Frontiers in Immunology",
issn = "1664-3224",
publisher = "Frontiers Media S.A.",

}

Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment. / Schepers, Melissa; Tiane, Assia; Paes, Dean; Sanchez, Selien; Rombaut, Ben; Piccart, Elisabeth; Rutten, Bart P. F.; Brone, Bert; Hellings, Niels; Prickaerts, Jos; Vanmierlo, Tim.

In: Frontiers in Immunology, Vol. 10, 1727, 24.07.2019, p. 1-17.

Research output: Contribution to journalReview articleAcademicpeer-review

TY - JOUR

T1 - Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment

AU - Schepers, Melissa

AU - Tiane, Assia

AU - Paes, Dean

AU - Sanchez, Selien

AU - Rombaut, Ben

AU - Piccart, Elisabeth

AU - Rutten, Bart P. F.

AU - Brone, Bert

AU - Hellings, Niels

AU - Prickaerts, Jos

AU - Vanmierlo, Tim

PY - 2019/7/24

Y1 - 2019/7/24

KW - multiple sclerosis

KW - phosphodiesterase

KW - neuroinflammation

KW - CNS repair

KW - remyelination

KW - BLOOD-BRAIN-BARRIER

KW - EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS

KW - CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES

KW - DISEASE NEUROFIBRILLARY CHANGES

KW - GUANYLATE-CYCLASE ACTIVITY

KW - APP/PS1 TRANSGENIC MICE

KW - PROTEIN-KINASE-A

KW - R6/2 MOUSE MODEL

KW - ALZHEIMERS-DISEASE

KW - OXIDATIVE STRESS

U2 - 10.3389/fimmu.2019.01727

DO - 10.3389/fimmu.2019.01727

M3 - Review article

VL - 10

SP - 1

EP - 17

JO - Frontiers in Immunology

JF - Frontiers in Immunology

SN - 1664-3224

M1 - 1727

ER -