Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment

Melissa Schepers, Assia Tiane, Dean Paes, Selien Sanchez, Ben Rombaut, Elisabeth Piccart, Bart P. F. Rutten, Bert Brone, Niels Hellings, Jos Prickaerts, Tim Vanmierlo*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Original languageEnglish
Article number1727
Pages (from-to)1-17
Number of pages17
JournalFrontiers in Immunology
Volume10
DOIs
Publication statusPublished - 24 Jul 2019

Keywords

  • multiple sclerosis
  • phosphodiesterase
  • neuroinflammation
  • CNS repair
  • remyelination
  • BLOOD-BRAIN-BARRIER
  • EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
  • CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES
  • DISEASE NEUROFIBRILLARY CHANGES
  • GUANYLATE-CYCLASE ACTIVITY
  • APP/PS1 TRANSGENIC MICE
  • PROTEIN-KINASE-A
  • R6/2 MOUSE MODEL
  • ALZHEIMERS-DISEASE
  • OXIDATIVE STRESS

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