Targeting PDGF-mediated recruitment of pericytes blocks vascular mimicry and tumor growth

Victor L. J. L. Thijssen, Yvette W. J. Paulis, Patrycja Nowak-Sliwinska, Katrin L. Deumelandt, Kayoko Hosaka, Patricia M. M. B. Soetekouw, Anca M. Cimpean, Marius Raica, Patrick Pauwels, Joost J. van den Oord, Vivianne C. G. Tjan-Heijnen, Mary J. Hendrix, Carl-Henrik Heldin, Yihai Cao, Arjan W. Griffioen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)447-458
Number of pages12
JournalJournal of Pathology
Volume246
Issue number4
DOIs
Publication statusPublished - Dec 2018

Keywords

  • tumor angiogenesis
  • imatinib
  • endothelial cells
  • melanoma
  • Ewing sarcoma
  • perivascular cells
  • vasculogenic mimicry
  • vessel stabilization
  • cancer
  • TO-MESENCHYMAL TRANSITION
  • STEM-LIKE CELLS
  • PRIMARY CUTANEOUS MELANOMA
  • ANTI-ANGIOGENIC THERAPY
  • VASCULOGENIC MIMICRY
  • ENDOTHELIAL-CELLS
  • BREAST-CANCER
  • CO-OPTION
  • IN-VIVO
  • METASTASIS

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